Authors
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Evaluating the Efficacy of Paxlovid in High-Risk Patients with Pre-Existing ImmunityJohn McLaughlin, PhD, examines high-risk individuals with prior SARS-CoV-2 immunity and presents that Paxlovid reduces the risk of hospitalization, death, and severe symptoms, highlighting its ongoing value for high-risk patients in a post-peak pandemic landscape.
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Considerations for Antimicrobial Stewardship While Optimizing Therapy for a Patient With HIVHere is a case study involving a patient with the virus and the clinical approach in thinking about appropriate treatment while keeping stewardship in mind.
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Internal Tremors: Adding to the List of Long COVID SymptomsInternal tremors are a newly recognized and troubling symptom of Long COVID, experienced by over one-third of participants in a Yale-based study
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Discussing Outpatient COVID-19 TreatmentsHere is a look at some of the treatment alternatives, which can offer simpler logistics and cost considerations.
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The Role of Rifampin in Bone and Joint InfectionsIn the latest column from the Society of Infectious Diseases Pharmacists (SIDP), here is a discussion on the use of rifampin as an adjunctive antibiotic treatment for patients with diabetic foot osteomyelitis.
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Clarametyx Biosciences Initiates Phase 2a Trial for CMTX-101 in Cystic Fibrosis PatientsDavid Richards emphasized the therapy’s potential to enhance antibiotic effectiveness by targeting bacterial biofilms, a significant challenge in treatment.
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Updates and Controversies in Necrotizing Soft Tissue InfectionsChanges in microbiology and antimicrobial resistance patterns warrant reevaluation of our current therapies for this condition.
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Due to FDA Policy Change, Fecal Microbiota Transplants Are in a Tenuous PositionThe country’s largest fecal distributor, OpenBiome, could be prevented from offering the product next year if the FDA does not approve the product used for fecal microbiota transplants to treat fulminant C difficile.
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Antibiotic Stewardship Programs Help Curb Superbug Threat by Leveraging DataThe OASIS platform will help outpatient facilities use prescribing data to improve patient care.
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A Clinician’s Perspective on Rebyota for Recurrent C Diff TreatmentTimothy Ritter, MD, provides his insights on using the live biotherapeutic product and what both patients and clinicians can expect in terms of safety and efficacy.
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What's New In 2024: From the CLSI Subcommittee on Antimicrobial Susceptibility TestingThe Clinical and Laboratory Standards Institute (CLSI) Subcommittee on Antimicrobial Susceptibility Testing had its series of meetings to update breakpoints for a variety of classes of antimicrobials.
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Nonventilator Hospital-Acquired Pneumonia: Epidemiology, Prevention, and Where It Is NowThe management of hospital-acquired pneumonia requires use of preventive bundles, mitigative of risk factors, and prompt diagnosis with initiation of treatment when highly suspected.
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The Impact of Widespread RSV Vaccination and Quantifying ResultsIn the fourth and final episode, the clinicians speak of the need for greater uptake of the RSV vaccines, overcoming an "RSV identity crisis," and the potential ancillary benefit of reducing bacterial infections.
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Fluoroquinolone Safe for Treating Severe Refractory M Pneumoniae PneumoniaInvestigators asked the children’s parents about the history of musculoskeletal-related disease, observed the children’s gait, and performed physical examinations.
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Navigating the Challenges of CMS AUR Reporting Mandates: Penalties, Progress, and PitfallsThe long-term benefits of antimicrobial use and resistance (AUR) reporting is about improving patient care and combating resistance.
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Examining the HIV Treatment PipelineA review of selected investigational long-active treatment options for HIV.
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Do Antibiotic Adverse Effects Affect Prescribing Practices?A focus group study reviewed provider practices to learn more about patient management and explore the potential to follow up with clinicians on important takeaways.
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Improving the Diagnosis of Intracardiac InfectionsThis technology is effective in cases that are difficult to diagnose.
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Invasive Nontyphoidal Salmonellosis: An Antimicrobial-Resistant FoeSalmonella becomes more dangerous as antimicrobial resistance grows. Read about its most common manifestations.
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Lessons in Resilience: What HIV Teaches Us About COVID-19Four lessons learned from the AIDS crisis that can be applied to the fight against our current pandemic.
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Final Diagnosis: Donor-Derived Staphylococcus Iugdunensis Endocarditis of Transplanted Heart"This case gives uncomfortable insight into a gap in early detection of infections in immunocompromised, high-risk patient populations. "
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Cefiderocol’s Role in Managing Carbapenem-Resistant Acinetobacter baumannii InfectionsThis agent is likely best utilized as part of a combination when treating this bacterium but data regarding appropriate combinations are scarce.
