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Latest:
Vancomycin AUC Implementation in Resource-Limited Settings and its Associated DifficultiesThe latest article from SIDP illustrates the challenges of area under the curve (AUC) implementation and offers insights for strategies and resources to overcome them.
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Multidrug Resistance in a Patient With HIVIn this case study, clinicians review a challenging case.
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Daptomycin Resistance Among Enterococci Is a Growing Antimicrobial Resistance ThreatIn a world heavily focused on therapeutic options for multidrug-resistant gram-negative organisms, the emergence of antimicrobial resistance among enterococci is often an under-recognized risk.
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Measles: An Old Foe Has ReturnedTexas is experiencing its largest measles outbreak in 30 years and the Centers for Disease Control and Prevention's (CDC) Epidemic Intelligence Service is providing support there. Here is an overview on testing, disease presentation, and vaccination, as well as commentary on the public health impact of vaccine hesitancy, and the unintended consequences of the immunization program’s success.
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Initial Findings from IMC-M113V Trial for HIV Functional Cure Strategy Shows PotentialBeatriz Mothe, MD, PhD discusses the Phase 1/2 STRIVE trial of IMC-M113V, a T cell receptor bispecific therapy targeting HIV-infected cells
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Penicillin and Syphilis Treatment: Sole Option or One of a Few?Penicillin continues to be an important therapy for treating syphilis. Here is a review of the literature in comparing one of the first antibiotics to non-penicillin treatments for non-neurological syphilis.
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A Case of Candida Albicans Ventriculitis Secondary to E Coli Ventriculoperitoneal Shunt InfectionRare cases of health care–associated meningitis and ventriculitis in adults caused by Candida species are associated with recent bacterial meningitis and broad-spectrum antibiotic use.
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Children, COVID-19, and Another Crazy Respiratory Viral SeasonKevin J. Downes, MD, and Contagion® Section Editor Conan MacDougall, PharmD, MAS, BCPS, BCIDP, discuss these important topics as another season approaches.
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Immunocore Reports Some PWH Achieve Viral Control and Dose-Dependent Active HIV Reservoir Reduction in IMC-M113V TrialDavid Berman, MD, PhD, discusses signs of dose-dependent viral control and reduction in active HIV reservoir in Phase 1/2 STRIVE trial data.
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The CM Study: Bivalent HIV Vaccine Induces Stronger T Cell Responses in People with HIV on ARTNilu Goonetilleke, LLBHons, BScHons, PhD, presents findings showing the bivalent HIVconsvX vaccine targets both Mosaic-1 and Mosaic-2, resulting in broader immune responses.
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Political and Social Barriers to Ending the HIV EpidemicLearning about these barriers is the first step to overcoming them.
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5 Ways Pharmacists Can Use Social Media For Professional AdvancementSocial media involves information and content sharing and pharmacists can utilize the various platforms to enhance their professional needs and resources for their careers.
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A Late-Stage Tuberculosis Vaccine is Making its Way Through Clinical TrialsMonday is World Tuberculosis (TB) Day, and a vaccine developed by the Gates Medical Research Institute is being studied in a phase 3 trial. If approved, the vaccine could potentially prevent pulmonary TB in adults and adolescents.
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CRAB-By No More?Understanding the potential and limitations of new Acinetobacter baumannii active therapies.
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A Comparative Analysis Show Distinct Severity of COVID-19 vs InfluenzaResults of a study by Yan Xie and colleagues highlight the severe impact of COVID-19, with higher death rates, increased risks of long-term complications, and greater infectivity compared to seasonal influenza.
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Addressing Antimicrobial Resistance in WomenUzma Syed, MD, DO discussed how various factors increase women’s susceptibility to AMR, the importance of policies, and the need for culturally specific education and advocacy to improve health outcomes.
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Fungal Biofilm-Related Diseases: Diagnosis, Treatment, and Emerging ChallengesProfessor Gordon Ramage, BSc, PhD, discusses the increasing impact of fungal biofilms, new treatment options, and the need for enhanced detection methods.
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Analyzing Household Transmission of COVID-19At ID Week 2024, an investigator, Amanda M. Casto, MD, PhD, discusses her work on the CASCADIA study, which examined infection rates in this setting, and how it challenged assumptions that there is likely a singular carrier bringing viruses into homes.
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Timeline for mRNA Vaccine Development for Rift Valley FeverCaryn Fenner and Petro Terblanche outline Afrigen's clinical trial plans, local partnerships, and vaccine pipeline.
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Final Thoughts on COVID-19 and FluFinal thoughts from experts on controlling COVID-19 and influenza.
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Tricky Infusion Issues and Potential Solutions: OPAT EditionOutpatient parenteral antimicrobial therapy (OPAT) offers benefits for patients as well as providing cost effectiveness; however, it is not without its challenges. Two clinicians provide insights on this modality.
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Apretude PrEP Shows High Efficacy, Safety in Diverse StudiesNew data at CROI 2025 shows zero cases of HIV acquisition reported with Apretude (cabotegravir long-acting (CAB LA) for PrEP in varied clinical settings and populations in 2 implementation studies in the US and Brazil.
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Antimicrobial Stewardship: How to Extend a Solid HandshakeIn the latest column from SIDP, handshake stewardship prioritizes face-to-face communication between frontline providers to enable feedback to assess the appropriateness of prescribed antimicrobials.
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Expanding Tick-Borne Disease Trends in New JerseyEvelyn Wu, MD, reveals a rise in tick-borne diseases in New Jersey over the past two decades and correlations with the influence of warming climate conditions.
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Shifting to Shorter Courses of Antibiotic Therapy for Common Pediatric InfectionsIn the latest SIDP column, two clinicians provide information on recent studies and guidelines directed at antibiotic durations in this patient population.
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A Case of Hemophagocytic Lymphohistiocytosis Secondary to Cytomegalovirus InfectionThere have been sporadic cases Hemophagocytic Lymphohistiocytosis, associated with Cytomegalovirus Infection infection, suggesting that CMV may cause clinically significant disease beyond mononucleosis in immunocompetent individuals.
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Impact of Inpatient Pharmacist Review of Discharge AntibioticsA food for thought as an ambulatory antibiotic stewardship initiative.
