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5 Strategies for Improving Sepsis Care ManagementHospitalists can be better equipped to identify patients most in need of intervention and standardize sepsis management efforts.
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Targeted Prophylaxis Reduces Hospital-Onset C difficile Infections in High-Risk PatientsThe STOP-CDI intervention presented by Matthew J.Ziegler, MD MSCE revealed using prophylactic enteral vancomycin, significantly reduced hospital-onset C difficile infections among immunocompromised patients.
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Climate Change Effects on Vector-Borne Disease: The Case of LymeWith evolving weather patterns, the natural habitat of ticks is expanding, and more people are becoming susceptible to them.
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Backpack Science: Enabling Realtime Work in the Field for Genomic Testing of Infectious DiseasesGathering data in the field, especially when it relates to infectious disease may have potentially profound implications for research because it enables scientists to generate valuable data quickly and efficiently without having to be in a laboratory setting.
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Stronger Than Yesterday: Decreased Hospital Readmissions After Strengthening of an OPAT ProgramAlthough close clinician monitoring is warranted to avoid complications for this this type of treatment, it can be beneficial to patients and help reduce care costs.
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Vancomycin AUC Implementation in Resource-Limited Settings and its Associated DifficultiesThe latest article from SIDP illustrates the challenges of area under the curve (AUC) implementation and offers insights for strategies and resources to overcome them.
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Multidrug Resistance in a Patient With HIVIn this case study, clinicians review a challenging case.
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Daptomycin Resistance Among Enterococci Is a Growing Antimicrobial Resistance ThreatIn a world heavily focused on therapeutic options for multidrug-resistant gram-negative organisms, the emergence of antimicrobial resistance among enterococci is often an under-recognized risk.
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Novavax vs mRNA Vaccines: Understanding Vaccine ReactogenicityNovavax Vice President Matthew Rousculp on reactogenicity, vaccine hesitancy, and supporting informed decisions.
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How Can Scientists and Investigators Find Funding Today?Rodney Rohde, PhD, SM(ASCP), SVCM, MBCM, FACSc, discusses the ongoing concerns about the federal government’s hold on funding for research and the potential chilling effect that it may have on laboratory professionals and deciding on careers, especially in areas such as public health. He also talks about locating and engaging in potential alternative resources for research funding.
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Initial Findings from IMC-M113V Trial for HIV Functional Cure Strategy Shows PotentialBeatriz Mothe, MD, PhD discusses the Phase 1/2 STRIVE trial of IMC-M113V, a T cell receptor bispecific therapy targeting HIV-infected cells
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Complicating the Uncomplicated: A Bundled Approach to Reducing Inappropriate Antibiotic Prescribing for Acute Uncomplicated BronchitisA recent study evaluated bundled ambulatory stewardship interventions (ASIs) — audits, reporting, webinars, and electronic alerts — to reduce inappropriate antibiotic prescriptions (IAPs) for acute uncomplicated bronchitis (AUB).
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A Case of Candida Albicans Ventriculitis Secondary to E Coli Ventriculoperitoneal Shunt InfectionRare cases of health care–associated meningitis and ventriculitis in adults caused by Candida species are associated with recent bacterial meningitis and broad-spectrum antibiotic use.
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Children, COVID-19, and Another Crazy Respiratory Viral SeasonKevin J. Downes, MD, and Contagion® Section Editor Conan MacDougall, PharmD, MAS, BCPS, BCIDP, discuss these important topics as another season approaches.
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Immunocore Reports Some PWH Achieve Viral Control and Dose-Dependent Active HIV Reservoir Reduction in IMC-M113V TrialDavid Berman, MD, PhD, discusses signs of dose-dependent viral control and reduction in active HIV reservoir in Phase 1/2 STRIVE trial data.
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The CM Study: Bivalent HIV Vaccine Induces Stronger T Cell Responses in People with HIV on ARTNilu Goonetilleke, LLBHons, BScHons, PhD, presents findings showing the bivalent HIVconsvX vaccine targets both Mosaic-1 and Mosaic-2, resulting in broader immune responses.
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Political and Social Barriers to Ending the HIV EpidemicLearning about these barriers is the first step to overcoming them.
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A Passion for Infectious Disease Education and CommunicationIn our latest podcast, Tim Gauthier, PharmD, BCPS, BCIDP, discusses all things pathogens and antibiotics. He also details the opportunities presented for antimicrobial stewardship when it combines diagnostics and treatment duration.
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A Late-Stage Tuberculosis Vaccine is Making its Way Through Clinical TrialsMonday is World Tuberculosis (TB) Day, and a vaccine developed by the Gates Medical Research Institute is being studied in a phase 3 trial. If approved, the vaccine could potentially prevent pulmonary TB in adults and adolescents.
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CRAB-By No More?Understanding the potential and limitations of new Acinetobacter baumannii active therapies.
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A Comparative Analysis Show Distinct Severity of COVID-19 vs InfluenzaResults of a study by Yan Xie and colleagues highlight the severe impact of COVID-19, with higher death rates, increased risks of long-term complications, and greater infectivity compared to seasonal influenza.
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Addressing Antimicrobial Resistance in WomenUzma Syed, MD, DO discussed how various factors increase women’s susceptibility to AMR, the importance of policies, and the need for culturally specific education and advocacy to improve health outcomes.
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Fungal Biofilm-Related Diseases: Diagnosis, Treatment, and Emerging ChallengesProfessor Gordon Ramage, BSc, PhD, discusses the increasing impact of fungal biofilms, new treatment options, and the need for enhanced detection methods.
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Analyzing Household Transmission of COVID-19At ID Week 2024, an investigator, Amanda M. Casto, MD, PhD, discusses her work on the CASCADIA study, which examined infection rates in this setting, and how it challenged assumptions that there is likely a singular carrier bringing viruses into homes.
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Timeline for mRNA Vaccine Development for Rift Valley FeverCaryn Fenner and Petro Terblanche outline Afrigen's clinical trial plans, local partnerships, and vaccine pipeline.
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Nationwide Avian Flu Response Gains Momentum, Yet Urgent Action Remains EssentialThe ongoing H5N1 avian flu outbreak has severely impacted U.S. poultry and dairy industries, prompting a $1 billion USDA response strategy that includes biosecurity, vaccination research, and innovation funding. With growing concern over viral mutations affecting humans and livestock, rapid, field-based diagnostic tools offer critical support in accelerating detection and containment efforts.
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Federal Government Changes Course Again on COVID-19 Vaccine PolicyAfter the leaders of the NIH, FDA, and HHS made an announcement stating that both pregnant women and children were going to be taken off the COVID-19 immunization schedule, they decided to offer a new designation for the latter group, making it a shared decision between providers and patients.
