Authors
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Sepsis Awareness Month: Highlighting the Findings from BLINGIIIContinuous antibiotic infusions show positive results and may improve outcomes for patients with severe sepsis.
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Differentiating Between DNA and mRNA PlatformsAmi Patel, PhD, provides insights on both technologies and how her research center, the Wistar Institute, is involved in DNA vaccine and monoclonal antibody research.
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Sticking It to COVID-19: The Expansion of the Pfizer-BioNTech Vaccine EUAA review of the data and circumstances that led to authorization in children ages 5 to 11 years.
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So You Made the Decision to Implement Vancomycin AUC Dosing. Now What?Since the vancomycin guideline update, institutional leaders have been faced with the challenge of implementing and monitoring AUC-guided dosing.
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Final Diagnosis: Donor-Derived Staphylococcus Iugdunensis Endocarditis of Transplanted Heart"This case gives uncomfortable insight into a gap in early detection of infections in immunocompromised, high-risk patient populations. "
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Hepatitis C Linked to Increased Risk of Peripheral Artery Disease in Hemodialysis PatientsHCV infection was associated with elevated brachial-ankle pulse wave velocity levels in patients with ESRD receiving hemodialysis.
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Preparing for the Next Long-acting AntiretroviralsClinicians can make room for infrequent treatment options as patients enjoy their daily lives.
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Gilead and Merck Report Successful Phase 2 Results for Investigational Once-Weekly HIV TreatmentThe combination of the antiviral agents islatravir and lenacapavir demonstrates both efficacy and safety, leading to advancement into Phase 3 trials.
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Tips for Talking with Patients about Fecal Microbiota Transplant for Recurrent C. difficile InfectionsTo close the discussion, experts on C. difficile infections discuss how they talk with patients about fecal microbiota transplantation.
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Echinocandin Dosing Considerations in Obese Patients: A ReviewObesity significantly impacts the pharmacokinetics (PK) of antifungal drugs like echinocandins, including volume of distribution (Vd) and clearance. However, despite these PK differences, current clinical evidence generally does not support the need for universal dose adjustments in obese patients. Clinicians should consider personalized dosing based on patient characteristics, infection severity, and specific drug properties due to echinocandins' favorable safety profiles.
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COVID-19 Impact on Antimicrobial Stewardship: Consequences and Silver LiningsThis crisis has united multidisciplinary groups and laid the foundation to better equip the health care workforce for future pandemics.
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Combination Hepatitis C Therapy Efficacious in Those With Previously Untreated Acute InfectionTreatment with glecaprevir/pibrentasvir (G/P) demonstrated a virologic response at post-treatment week 12, which was superior to the prior efficacy threshold.
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Starting an Inpatient Penicillin Skin Testing Service in 2023Patients with a penicillin allergy can be safely delabeled using minimal resources, opening up treatment options.
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INSPIRE Trials: Reducing Antibiotic Prescribing For Skin and Soft Tissue And Abdominal InfectionsLed by Shruti K. Gohil, MD, MPH, the trials examined how computerized physician order entry prompts can reduce the use of extended-spectrum antibiotics in hospitalized patients while maintaining patient safety.
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Infectious Diseases Provider Role in Extracorporeal Membrane Oxygenation InfectionsThere has been an emergence of extracorporeal membrane oxygenation-associated infections. Here is a review of how to define them and clinical management of this heterogeneous syndrome.
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All About the JUICE: Justifying Use of Non-Carbapenems for Infected NeCrotizing PancrEatitisManagement of this condition has been associated with antibiotic misuse. In the latest Bench to Bedside column, clinicians offer insights on therapy indications and what the latest literature reports on the condition.
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The Role of Rifampin in Bone and Joint InfectionsIn the latest column from the Society of Infectious Diseases Pharmacists (SIDP), here is a discussion on the use of rifampin as an adjunctive antibiotic treatment for patients with diabetic foot osteomyelitis.
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What You Need to Know About 3 Rare Infectious Eye DiseasesEric D. Donnenfeld, MD, discusses 3 uncommon yet highly infectious eye diseases, emphasizing the importance of timely treatment and preventative measures.
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What’s New With Non–COVID-19 VaccinesAlthough COVID-19 vaccination remains the primary focus for health care, other paramount vaccines need to be recognized. Here is a review.
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Fluoroquinolone Safe for Treating Severe Refractory M Pneumoniae PneumoniaInvestigators asked the children’s parents about the history of musculoskeletal-related disease, observed the children’s gait, and performed physical examinations.
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Barriers to Health Care Transition in Adolescents and Young Adults With Early Acquired HIV InfectionUnique challenges can affect the success of the shift from pediatric to adult care settings.
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Multidisciplinary Perspectives on HIV TreatmentA multidisciplinary panel concludes a discussion on best practices for managing patients with HIV in various healthcare settings and overcoming social health disparities.
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Global Action Against AMRTina Tan, MD, FAAP, FIDSA, FPIDS underscores the importance of education and global collaboration in antimicrobial stewardship to tackle the escalating threat of AMR, and her takeaways from the UN General Assembly High-Level Meeting on Antimicrobial Resistance.
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What We Know But Still Have to Learn About Long COVIDDespite advances in understanding and treating Long COVID, many questions about its mechanisms, susceptibility, and varied recovery patterns remain unresolved, underscoring the need for continued research.
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Resources Available for Patients with HIV Drug ResistanceThe panel concludes its discussion by talking about resources available for providers in managing their patients with HIV who experience drug resistance.
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Examining RSV Vaccines for SeniorsTwo RSV vaccines for seniors were FDA approved this year and here is an overview of the vaccines and the study data.
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Antimicrobial Stewardship: More Is BetterA robust stewardship program requires a comprehensive investment in technology and staff.
