Authors
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2024 S aureus and MRSA Trials: Key TakeawaysJeffrey Freiberg, MD, PhD review of the SABATO trial on oral antibiotics for S aureus bacteremia and a comparison of mupirocin and iodine treatments for MRSA decolonization.
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Assisting With International Health Care NeedsAlthough the pandemic halted many medical mission assignments, these opportunities and others are becoming available to help those geographic areas with acute needs.
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Should Cefazolin be Prescribed in Patients With B-lactam Allergies?For patients undergoing surgery, looking at the potential benefits of this antimicrobial for prophylaxis.
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National Youth HIV/AIDS Awareness Day Reminds Young People They Are Not ForgottenDuring these uncertain times, RAIN President and CEO Chelsea Gulden talks about the importance of taking a grassroots approach to HIV advocacy to work with young people in the local communities who are either dealing with the virus or are susceptible to it.
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Maternal RSV Vaccines Show Promise for Infant Protection but Raise Safety ConcernsNew meta-analysis at the 2025 vaccinology conference highlights the efficacy of maternal RSV vaccines, with calls for enhanced monitoring following safety issues with one candidate
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IMUNON’s IMNN-101 Vaccine Shows Promising Results in Phase 1 Trial, Demonstrates Cross-Reactivity Against COVID VariantsStacy Lindborg, PhD, highlights the vaccine’s immune response, safety, and global distribution potential.
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Strategies for Improving Pandemic PreparednessSyra Madad, DHSC, MSc, MCP, CHEP, outlines early surveillance systems and diagnostic innovations for enhancing pandemic management and response.
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Defining the Characteristics of Breakthrough Invasive Fungal Infections in Hematologic DisordersThis systematic review focuses on breakthrough invasive fungal infections (bIFIs) in patients with high-risk hematological cancers, like acute leukemia, or those who have undergone stem cell transplants. Despite prophylactic antifungal treatments (usually with voriconazole or posaconazole), bIFIs remain challenging due to their complexity and high mortality rates.
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Simplifying Vaccine Access Translates to Better UptakeInvestigators evaluated strategies to simplify the vaccination process to yield higher rates of adult immunization, similar to that of the COVID-19 pandemic.
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Candida auris: Coming Soon to a Facility Near You?Epidemiologic and clinical lessons for the uninitiated.
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Multidrug Resistance in a Patient With HIVIn this case study, clinicians review a challenging case.
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Rifaquizinone: A Novel Rifamycin-Quinolone Hybrid AntibioticRifaquizinone is a dual-pharmacophore antibiotic combining rifamycin and a fluoroquinolone-like compound, showing strong bactericidal activity against resistant Staphylococcus aureus strains and biofilms, with promising results for treating prosthetic joint infections (PJI) but limited oral bioavailability.
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The Next Generation of COVID-19 Vaccines and BoostersWill there be an answer to keep the continuously evolving virus at bay? Are seasonal combination vaccines the wave of the future?
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Funding Isn’t Everything: Bringing Pharma to the Table for the Pasteur ActThe pharmaceutical industry faces challenges when investing in new antibiotics, which emphasizes the need for regulatory reforms, incentives, and collaborative efforts between government, healthcare organizations, and private companies. The prospective bill, the Pasteur Act, is one potential strategy to help in these areas, and incentivize pharmaceutical companies to develop these essential therapies.
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That’s Not Appropriate: A Look at Antibiotic Prescribing Post DischargeExtending antimicrobial stewardship programs to transition of care and discharge may prove beneficial to reduce unnecessary antibiotic use.
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Health Equity is Essential to Overcoming Antimicrobial ResistanceThe antimicrobial resistance (AMR) crisis stems from natural microbial adaptation and the lack of new antimicrobials in development. Vulnerable populations worldwide, including within the US, are disproportionately affected, exacerbating the spread of resistance.
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Top 5 Infectious Disease News Stories Week of June 28-July 5This week, Moderna’s mRNA-1010 flu vaccine showed strong phase 3 results, new research reveals that FMT may fail due to functional mismatches between donor microbes and the recipient’s gut, and more.
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Sticking It to COVID-19: The Expansion of the Pfizer-BioNTech Vaccine EUAA review of the data and circumstances that led to authorization in children ages 5 to 11 years.
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Opposing Forces During COVID-19: Perspective From the ICUConflicting priorities of infection control, antimicrobial stewardship, and critical care make the management of sepsis secondary to SARS-CoV-2 infection challenging.
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Opposing Forces During COVID-19: Perspective From the ICUConflicting priorities of infection control, antimicrobial stewardship, and critical care make the management of sepsis secondary to SARS-CoV-2 infection challenging.
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Lifting the Medical and Economic Burden of AMR in the USThis bipartisan initiative highlights the need for a comprehensive approach to combat antimicrobial resistance (AMR), incorporating both antibiotic drug development and increased funding for stewardship programs.
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Febrile Finesse: Are We Employing Appropriate Empiric Coverage in Patients With Neutropenic Fever?Traditional therapy coverage does not include recent data that offers some updates in evaluating the current effectiveness of empiric antibiotic treatment.
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SHARE the Responsibility of Antibiotic Stewardship With Our PatientsHow pharmacists can use shared decision-making to improve antibiotic use.
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Updates in the Treatment of Mycobacterium TuberculosisThe latest Bench to Bedside column reviews new guidance on the treatment of drug-susceptible and drug-resistance Mycobacterium tuberculosis infections.
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Key Takeaways on FMTs in the Treatment of CDIExperts provide practice pearls for educating patients on and using FMTs for the management of CDI.
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The Next Generation of COVID-19 Vaccines and BoostersWill there be an answer to keep the continuously evolving virus at bay? Are seasonal combination vaccines the wave of the future?
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Lessons in Resilience: What HIV Teaches Us About COVID-19Four lessons learned from the AIDS crisis that can be applied to the fight against our current pandemic.
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New Antifungal Drug Olorofim Shows Efficacy in Treating Resistant Fungal InfectionsJohn Rex, MD, FACP, discusses the promise, precision, and challenges of this first-in-class antifungal following phase 2b trial results.
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Second-Generation Antifungal Aims to Address Invasive Fungal DiseaseScynexis developed its investigational fungal compound, SCY-247, which is in phase 1 clinical trials, and the company expects to share top-line data this year.
