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Community-Acquired Candida Glabrata Empyema: An Atypical Diagnosis Not to MissAlthough this patient had none of these common risk factors associated with Candida empyema, she did have other factors predisposing her to fungal colonization and subsequent infection.
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GigaGen's New Contract with BARDA for Polyclonal Antibody DevelopmentCarter Keller discusses the company's recent $135.2 million contract with BARDA to develop recombinant polyclonal antibody therapies targeting botulinum neurotoxins and an unspecified biothreat, highlighting their innovative approach to address emerging health threats.
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COVID-19 Booster Shots and the FutureKey opinion leaders provide some advice for the public regarding COVID-19 booster shots and look to the future of the pandemic.
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Oral Carbapenems: Promise, Peril, and PushbacksHere is a review of the literature for this class of antibiotics.
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What’s New With Non–COVID-19 VaccinesAlthough COVID-19 vaccination remains the primary focus for health care, other paramount vaccines need to be recognized. Here is a review.
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Lessons in Resilience: What HIV Teaches Us About COVID-19Four lessons learned from the AIDS crisis that can be applied to the fight against our current pandemic.
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Still Learning: Optimizing the Diagnosis and Screening of Respiratory VirusesWhile the COVID-19 pandemic has helped advance respiratory diagnostics and surveillance, there are still many gaps that remain across the spectrum of healthcare.
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Antimicrobial Stewardship: More Is BetterA robust stewardship program requires a comprehensive investment in technology and staff.
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SHARE the Responsibility of Antibiotic Stewardship With Our PatientsHow pharmacists can use shared decision-making to improve antibiotic use.
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A Day Late and a Dollar Short: Managing Antimicrobial Drug ShortagesWith antimicrobial drug shortages expected to continue globally, developing mitigation strategies is essential to prevent complications, including antimicrobial resistance.
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Practice Pearls for Treatment of Respiratory InfectionsTina Tan, MD; Wendy Wright, DNP, ANP-BC, FNP-BC, FAANP, FAAN, FNAP; Priya Nori, MD; Jacinda Abdul-Mutakabbir, PharmD; and Kevin Michael Reiter, MD, PA, provide key takeaways from the discussion on the treatment of respiratory viral infections.
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Multidisciplinary Perspectives on HIV TreatmentA multidisciplinary panel concludes a discussion on best practices for managing patients with HIV in various healthcare settings and overcoming social health disparities.
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The Pendulum of Progress: Soft Skills in Whole Person Clinical TrainingThese skills are as critical as ever, and younger clinicians and learners need them to communicate and work professionally.
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The Role of Antimicrobial Stewardship in the Treatment of C difficileBiologics have become a novel treatment in recurrent C. difficile.
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Challenges in the Management of Mycobacterium abscessus ComplexThis pathogen is the third most frequently isolated nontuberculous mycobacteria seen in the United States. Here is a review of how it presents and treatment options.
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Supporting Patients With HIVAdvice to community physicians regarding ways to enhance patient-provider relationships and navigate barriers that impact the management of HIV infections.
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Correcting the Lack of Diversity in Clinical Trials With Community-Based StudiesAmmara Mushtaq, MD, discusses the underrepresentation of different races during the pandemic, but also the newer efforts to include and represent these communities in smaller, local studies.
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Optimizing Antibiotic Use by Limiting Total Antibiotic ExposureShorter durations of antibiotic therapy demonstrate similar efficacy and may improve safety compared with longer courses for certain infections.
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Reduced-Dose Trimethoprim-Sulfamethoxazole Effective in Treating Mild to Moderate Pneumocystis jirovecii PneumoniaHere is a review of using this therapy in this patient population.
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In These COVID 19 Times, Can We Reduce Hospitalizations Due to Skin Infections?Shortages of health care workers and an increase in COVID-19 cases has put a severe strain on the health care system. Thus, the opportunity to reduce the hospitalizations for other conditions and expand outpatient treatment opportunities should be welcomed.
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Reducing Peripheral Venous Catheter InfectionsLack of data may mean bloodstream infections caused by PVCs are an overlooked cause of morbidity in hospitalized patients.
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Kalihinol Analog Targets Apicoplast Function In Malaria TreatmentKarine G. Le Roch, PhD, discussed her research on a kalihinol analog that combats drug resistance in malaria, emphasizing the need for innovative treatments in the context of climate change and rising transmission rates.
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Final Diagnosis: Pott Puffy Tumor With Subdural EmpyemaA rare case of Pott puffy tumor occurs in an atypical patient with no risk factors, likely due to untreated sinus infection.
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Evaluating Safety and Efficacy of Vaxart's Oral Vaccine's Impact on COVID-19 VariantsPart 2 with James F Cummings, MD, as he discusses the need for a stronger response to emerging variants, the importance of protecting high-risk populations, and the potential to reduce vaccine hesitancy through easier administration.
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“Triple Therapy” Facing Triple ThreatClinicians provide an overview of intraamniotic infections and offer treatment strategies for these challenging infections.
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The Underlying Threat of Multidrug-Resistant Pathogens in the COVID-19 EraOver half of patients admitted with positive SARS-CoV-2 testing received antibiotics, but evidence of bacterial infection is uncovered in far fewer cases. We may already be seeing the effects of antibiotic overprescribing.
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Biden Administration Unveils HCV Initiative: A Significant Step Towards Public HealthThe federal government is working to provide greater access to testing and treatment.
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Shifting to Shorter Courses of Antibiotic Therapy for Common Pediatric InfectionsIn the latest SIDP column, two clinicians provide information on recent studies and guidelines directed at antibiotic durations in this patient population.
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A Common Health Habit May Lower Rates of Pneumonia, ICU MortalityThe data from these meta-analyses highlight the value of developing systems to promote daily toothbrushing among those who have been hospitalized and, particularly, those on mechanical ventilation.
