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Expanded Treatment Options for Multi-Drug Resistant Infections in ChildrenIn the latest article from SIDP, here is a look at therapy options addressing this emerging clinical challenge.
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How Do You Measure the Success of Your Stewardship Program?The challenging search for a metric that effectively evaluates an ASP’s direct impact on appropriate antimicrobial use and improved patient outcomes.
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First-Hand Insights into Treating Hepatitis C in PregnancyCatherine Chappell, MD, MSc, presents what we know so far, highlighting the safety and effectiveness of direct-acting antivirals, the importance of shared decision-making, and the need for patient-provider discussions to ensure informed choices about care.
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SURE1 and REASSURE Trials Paved Way for FDA Approval of OrlynvahCorey Fishman and Steven Aronin, MD, discussed trial highlights of Orlynvah for uncomplicated urinary tract infections and outlining plans to seek partners for a market launch to address antibiotic resistance and enhance patient treatment options.
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Respiratory Virus Season: Colds and COVID-19 UpdateWill this winter bring the feared twindemic of SARS-CoV-2 and influenza, or will another common infection reemerge?
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Expanding the Antibiotic Stewardship Team Can Lead to Greater Adoption of PracticesThere is value in leveraging the contributions of nurses, laboratorians, and informaticists in antimicrobial stewardship.
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The NanoVax Vaccine Platform: Pandemic Preparedness and the Role of Mucosal ImmunityChad Costley, MD, MPH, discussed the platform's ability to respond to emerging respiratory diseases and the challenges in advancing mucosal vaccine development for health preparedness.
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Looking Toward the Future of CDI ManagementClosing out their discussion on Clostridioides difficile infection, panelists share closing thoughts on novel pipeline therapies.
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A Viral Colonial Legacy: HIV, Monkeypox Emerged Due to Ongoing Colonial Viral NeglectSimilar to HIV, the colonial and postcolonial history is fundamental to the biology of this monkeypox outbreak.
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The 5 Topics Every Infectious Disease Learner Should Read About, At Least Once!In the latest Bench to Bedside column, clinicians provide information and resources on recommended topics learners should explore.
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Bacterial Coinfections Among US Patients With Coronavirus Disease 2019Implications for antimicrobial use and antimicrobial resistance.
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NDM-Producing E coli Harboring PBP Insert Variants Emerges as New ThreatAs with other metallo-β-lactamases, NDM is capable of hydrolyzing nearly all β-lactams, including carbapenems, and the search for the proper antimicrobials is challenging.
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A Tale of 2 Settings: How Outpatient Clinics Differ From Institutions in Delivering StewardshipKevin Nguyen, PharmD, offers some insights on some of the challenges in the outpatient setting with regards to stewardship, and novel strategies being utilized.
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Examining RSV Vaccines for SeniorsTwo RSV vaccines for seniors were FDA approved this year and here is an overview of the vaccines and the study data.
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Varicella Zoster Virus and Human Papillomavirus Vaccination in Immunocompromised PatientsVaccination for VZV and HPV requires special consideration in immunocompromised patients. They are at risk for more severe viral illnesses if not immune, but they may also have decreased response to, and increased adverse effects from, vaccines.
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Optimizing Vancomycin Therapy: A Review of AUC Calculation TechniquesThe ideal parameter for vancomycin monitoring is the area under the curve, which can be calculated using pharmacokinetic equations or Bayesian software.
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COVID-19 Impact on Antimicrobial Stewardship: Consequences and Silver LiningsThis crisis has united multidisciplinary groups and laid the foundation to better equip the health care workforce for future pandemics.
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Questions Linger Around COVID-19’s OriginA preview of our August 2021 issue Chairman’s Letter.
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Optimizing Vancomycin Therapy: A Review of AUC Calculation TechniquesThe ideal parameter for vancomycin monitoring is the area under the curve, which can be calculated using pharmacokinetic equations or Bayesian software.
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Ready, Set, Cabenuva: Implementing Cabotegravir/RilpivirineThis novel therapeutic option represents the first long-acting injectable approved for maintenance of HIV-1 suppression.
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PEN-FAST Forward: Accelerating Penicillin Allergy De-LabelingPEN-FAST is a validated risk stratification tool that promotes efficient, safe, and effective de-labeling of penicillin allergies.
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Safety of Cefazolin Has Been Underestimated for GBS Prophylaxis During LaborBoth undertreatment and overtreatment were common in this cohort of penicillin-allergic pregnant women with Group B Streptococcus (GBS).
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Gender-Affirming Care in Persons Living With HIVGender-affirming hormone therapy (GAHT) therapy consists of administration of exogenous hormones and suppression of endogenous hormone production, with the goal of obtaining characteristics more congruent with an individual’s gender identity. Here is a review of these therapies and consideration for PrEP and the risks associated with HIV in this diverse population.
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Trends in Carbapenemase-Producing Organisms: Prevalence, Treatment, and OutcomesA study of carbapenemase-producing organisms found similar rates of infections, highlighting treatment challenges, the role of rapid diagnostics, and surveillance on antimicrobial stewardship due to high mortality rates.
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Outpatient Antimicrobial Stewardship: The Keys to Developing a Successful ProgramThis form of stewardship can reduce unnecessary antibiotic prescribing, reduce costs, and optimize patient outcomes.
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Pharmacotherapy Options for COVID-19: Does Fluvoxamine Have a Place in Therapy?The need for safe and effective treatment against the various strains of COVID-19 increase, and investigators continue to assess various pharmacologic options.
