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Sticking It to COVID-19: The Expansion of the Pfizer-BioNTech Vaccine EUAA review of the data and circumstances that led to authorization in children ages 5 to 11 years.
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Opposing Forces During COVID-19: Perspective From the ICUConflicting priorities of infection control, antimicrobial stewardship, and critical care make the management of sepsis secondary to SARS-CoV-2 infection challenging.
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Opposing Forces During COVID-19: Perspective From the ICUConflicting priorities of infection control, antimicrobial stewardship, and critical care make the management of sepsis secondary to SARS-CoV-2 infection challenging.
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Lifting the Medical and Economic Burden of AMR in the USThis bipartisan initiative highlights the need for a comprehensive approach to combat antimicrobial resistance (AMR), incorporating both antibiotic drug development and increased funding for stewardship programs.
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Febrile Finesse: Are We Employing Appropriate Empiric Coverage in Patients With Neutropenic Fever?Traditional therapy coverage does not include recent data that offers some updates in evaluating the current effectiveness of empiric antibiotic treatment.
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SHARE the Responsibility of Antibiotic Stewardship With Our PatientsHow pharmacists can use shared decision-making to improve antibiotic use.
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Updates in the Treatment of Mycobacterium TuberculosisThe latest Bench to Bedside column reviews new guidance on the treatment of drug-susceptible and drug-resistance Mycobacterium tuberculosis infections.
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Key Takeaways on FMTs in the Treatment of CDIExperts provide practice pearls for educating patients on and using FMTs for the management of CDI.
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The Next Generation of COVID-19 Vaccines and BoostersWill there be an answer to keep the continuously evolving virus at bay? Are seasonal combination vaccines the wave of the future?
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Lessons in Resilience: What HIV Teaches Us About COVID-19Four lessons learned from the AIDS crisis that can be applied to the fight against our current pandemic.
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Expanded Treatment Options for Multi-Drug Resistant Infections in ChildrenIn the latest article from SIDP, here is a look at therapy options addressing this emerging clinical challenge.
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How Do You Measure the Success of Your Stewardship Program?The challenging search for a metric that effectively evaluates an ASP’s direct impact on appropriate antimicrobial use and improved patient outcomes.
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First-Hand Insights into Treating Hepatitis C in PregnancyCatherine Chappell, MD, MSc, presents what we know so far, highlighting the safety and effectiveness of direct-acting antivirals, the importance of shared decision-making, and the need for patient-provider discussions to ensure informed choices about care.
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SURE1 and REASSURE Trials Paved Way for FDA Approval of OrlynvahCorey Fishman and Steven Aronin, MD, discussed trial highlights of Orlynvah for uncomplicated urinary tract infections and outlining plans to seek partners for a market launch to address antibiotic resistance and enhance patient treatment options.
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Early-Stage Antibiotic for Bone and Joint Infections Comparable to Standard of Care TherapyA small phase 2 study evaluated Debiopharm’s investigational antibiotic, afabicin, including its clinical response rate and safety profile of 2-3 weeks of treatment for staphylococcal bone and joint infections (BJI).
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Cautionary Tale Associated in Trial With Rare Error in Cox RegressionInflaRx CEO Niels Riedemann, MD, discusses the issue that arose and cost the company some of its data for its investigational therapy being studied for SARS-CoV-2-induced acute respiratory distress syndrome (ARDS).
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Pandemic Preparedness: How Immunomics Technology is Leading the WayThe COVID-19 pandemic underscored the urgent need for global pandemic preparedness. The World Health Organization (WHO) is leading efforts to establish a global treaty to address future pandemics, with findings expected in 2025. Central to this preparedness is immunomics, a field leveraging advanced genomics technologies to study the immune system at unprecedented levels of detail.
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Respiratory Virus Season: Colds and COVID-19 UpdateWill this winter bring the feared twindemic of SARS-CoV-2 and influenza, or will another common infection reemerge?
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Expanding the Antibiotic Stewardship Team Can Lead to Greater Adoption of PracticesThere is value in leveraging the contributions of nurses, laboratorians, and informaticists in antimicrobial stewardship.
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The NanoVax Vaccine Platform: Pandemic Preparedness and the Role of Mucosal ImmunityChad Costley, MD, MPH, discussed the platform's ability to respond to emerging respiratory diseases and the challenges in advancing mucosal vaccine development for health preparedness.
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HIV Prevention: Discussing PrEP, PEP, and Vaccine DevelopmentColleen Kelley, MD, MPH, offers some insights on where we are today with the state of HIV prevention including the expanding PrEP options, why PEP is underutilized, and the challenges behind HIV vaccine development.
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Looking Toward the Future of CDI ManagementClosing out their discussion on Clostridioides difficile infection, panelists share closing thoughts on novel pipeline therapies.
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A Viral Colonial Legacy: HIV, Monkeypox Emerged Due to Ongoing Colonial Viral NeglectSimilar to HIV, the colonial and postcolonial history is fundamental to the biology of this monkeypox outbreak.
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The 5 Topics Every Infectious Disease Learner Should Read About, At Least Once!In the latest Bench to Bedside column, clinicians provide information and resources on recommended topics learners should explore.
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Bacterial Coinfections Among US Patients With Coronavirus Disease 2019Implications for antimicrobial use and antimicrobial resistance.
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NDM-Producing E coli Harboring PBP Insert Variants Emerges as New ThreatAs with other metallo-β-lactamases, NDM is capable of hydrolyzing nearly all β-lactams, including carbapenems, and the search for the proper antimicrobials is challenging.
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Addressing Neonatal CNS Infections: Case Report of Ceftaroline Therapy in Preterm Infant With Ventriculosubgaleal ShuntHere is a novel use of ceftaroline to treat methicillin-resistant Staphylococcus epidermidis ventriculitis in a preterm infant with a ventriculosubgaleal shunt.
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Addressing Neonatal CNS Infections: Case Report of Ceftaroline Therapy in Preterm Infant With Ventriculosubgaleal ShuntHere is a novel use of ceftaroline to treat methicillin-resistant Staphylococcus epidermidis ventriculitis in a preterm infant with a ventriculosubgaleal shunt.
