Authors
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ALLIANCE Study: B/F/TAF Achieves Sustained HIV and HBV SuppressionAnchalee Avihingsanon, MD, PhD presents results showing 95.4% HIV RNA suppression and 86.6% HBV DNA suppression after 48 weeks of B/F/TAF in HIV-HBV co-infected patients.
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How a Prodrug Approach May Aid In Antimalarial DevelopmentSesh Sundararaman, MD, PhD, discusses his findings and how this approach can be triggered to minimize undesirable treatment features and open the door to newer treatment possibilities.
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What's New In 2024: From the CLSI Subcommittee on Antimicrobial Susceptibility TestingThe Clinical and Laboratory Standards Institute (CLSI) Subcommittee on Antimicrobial Susceptibility Testing had its series of meetings to update breakpoints for a variety of classes of antimicrobials.
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The Lingering Threat: Managing Severe COVID-19 in the Postpandemic EraAlthough COVID-19 has receded quite a bit from the minds of many, it still remains a virus that can present serious morbidity and mortality. Here is a review of clinical treatment strategies by an intensivist when seeing patients with severe COVID-19.
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Advancing STOP2030 Treatment in Global HealthAlejandro Krolewiecki, MD discusses the path to regulatory approval, collaboration with global health organizations, and the role of partnerships in scaling up the new treatment for neglected tropical diseases.
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The Impact of Widespread RSV Vaccination and Quantifying ResultsIn the fourth and final episode, the clinicians speak of the need for greater uptake of the RSV vaccines, overcoming an "RSV identity crisis," and the potential ancillary benefit of reducing bacterial infections.
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Fluoroquinolone Safe for Treating Severe Refractory M Pneumoniae PneumoniaInvestigators asked the children’s parents about the history of musculoskeletal-related disease, observed the children’s gait, and performed physical examinations.
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Navigating the Challenges of CMS AUR Reporting Mandates: Penalties, Progress, and PitfallsThe long-term benefits of antimicrobial use and resistance (AUR) reporting is about improving patient care and combating resistance.
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Examining the HIV Treatment PipelineA review of selected investigational long-active treatment options for HIV.
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Does Slow Viral Clearance and Viral Rebound During Infection Contribute to Long COVID?Annie Antar, MD, PhD, offers insights around her research on her findings on this subject.
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Do Antibiotic Adverse Effects Affect Prescribing Practices?A focus group study reviewed provider practices to learn more about patient management and explore the potential to follow up with clinicians on important takeaways.
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Improving the Diagnosis of Intracardiac InfectionsThis technology is effective in cases that are difficult to diagnose.
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Invasive Nontyphoidal Salmonellosis: An Antimicrobial-Resistant FoeSalmonella becomes more dangerous as antimicrobial resistance grows. Read about its most common manifestations.
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Lessons in Resilience: What HIV Teaches Us About COVID-19Four lessons learned from the AIDS crisis that can be applied to the fight against our current pandemic.
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Final Diagnosis: Donor-Derived Staphylococcus Iugdunensis Endocarditis of Transplanted Heart"This case gives uncomfortable insight into a gap in early detection of infections in immunocompromised, high-risk patient populations. "
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Cefiderocol’s Role in Managing Carbapenem-Resistant Acinetobacter baumannii InfectionsThis agent is likely best utilized as part of a combination when treating this bacterium but data regarding appropriate combinations are scarce.
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Pulmonary Coinfection With C neoformans and C immitis: A Novel Fungal CohabitationA patient presented with a history of uncontrolled HIV and a history of polysubstance use.
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Need for Speed: Rapid Antiretroviral Initiation in the Emergency DepartmentEmergency departments (EDs) are an important entry point into the health care system and have been identified as a location with opportunity for increased HIV diagnosis and management.
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Improving Screening, Management of Hepatitis C in Infants and ChildrenDespite hepatitis C (HCV) incidence rates increasing, adequate screening for the virus continues to be a pressing challenge for public health officials.
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Infectious Diseases Provider Role in Extracorporeal Membrane Oxygenation InfectionsThere has been an emergence of extracorporeal membrane oxygenation-associated infections. Here is a review of how to define them and clinical management of this heterogeneous syndrome.
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Antimicrobial Stewardship Can Help Prevent Injection Drug Use–Related InfectionsEscalating usage and more drug choices are putting more people at risk.
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World Polio Day: A Time to Reflect on Accomplishments, Acknowledge There’s Still Work to DoCarol Pandak, EdD, director of PolioPlus, Rotary International, discusses the significance of this day and efforts that continue around the world to work towards eradication of this disease.
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A Day Late and a Dollar Short: Managing Antimicrobial Drug ShortagesWith antimicrobial drug shortages expected to continue globally, developing mitigation strategies is essential to prevent complications, including antimicrobial resistance.
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HIV's Golden Age: Responding to the Needs of an Aging PopulationAs the cohort of people living with HIV in the US ages, HIV care programs must rapidly adapt to the changing needs of older adults with HIV.
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Detecting T Cell Dysfunction in Post-Acute Infection SyndromesNigel McCracken, PhD, presents a diagnostic test to identify early T cell dysfunction in syndromes like Long COVID and ME/CFS, aiming to improve treatment strategies before symptoms escalate.
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Exploring the Recently Approved and Upcoming Clostridioides difficile TherapeuticsThis market has seen a flurry of activity, as shown by a review of the latest agents.
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The Challenges of Hepatitis B Clinical Care Within Underserved CommunitiesIn the second part of their interview, Debika Bhattacharya, MD MSc, and Su H. Wang, MD, MPH, FACP, continue the conversation around the difficulties of getting people into care, and what the new hepatitis B guidelines hope to improve in this area.
