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New and Pipeline Antiretroviral Agents for the Treatment of HIV-1 InfectionThis article seeks to review newer ART agents, as well as those in later stages of drug development, for the treatment of HIV-1 infection.
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Will Brazil's Next Epidemic Come from Another Mosquito-Borne Virus?As researchers discover Chikungunya-carrying mosquitoes in Brazil, a new study analyzes the impact of the Zika virus on the area.
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Using IL-6 Inhibitors to Treat COVID-19Use of an IL-6 inhibitor has the potential to prevent the cytokine storm caused by severe COVID-19 infection.
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Clinicians Only Using New Antibiotics in Quarter of CRE Infection Cases, New Study FindsAs a growing number of infections become resistant to antibiotic medications, it is becoming crucially important that providers not only practice antibiotic stewardship but also use effective antibiotics when they are needed.
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Four Fungal Horsemen: Emerging Trends in Fungal Disease EpidemiologyNew public health perspectives on aspergillosis, sporotrichosis, histoplasmosis, and coccidioidomycosis.
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What the 2018 DRC Ebola Epidemic Taught Us About Outbreak Response and Experimental CountermeasuresHow has treating infections changed with the availability of experimental vaccines and therapeutics, and how can we apply this to COVID-19 today?
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A Peculiar Finding in an Unfamiliar PatientA rare metallo-ß-lactamase makes its way into the United States via an 84-year-old patient.
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Successful Stewardship Strategies in Long-Term Care FacilitiesOne successful model takes an engineering approach to patient safety outcomes focusing on work system improvements.
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ART Adherence in Transgender and Gender Nonconforming PeopleA recent study published in Transgender Health analyzed transgender and gender-nonconforming ART adherence based on the US Trans Survey, the largest survey of TGNC people in the United States.
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Fighting Flu: Managing and Preventing Influenza with AntiviralsTaking into account the severity of this flu season, it is important that health care providers understand and choose the best treatment option for each patient.
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Is Greater BSA Use for Sepsis, Bacteremia Affecting HO-CDIs?An examination of broad-spectrum antibiotic use in this patient population is essential for developing strategies to mitigate the risk of these infections.
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Antiretroviral Stewardship: The Time is NowIn this narrative review of studies evaluating antiretroviral stewardship programs (ARVSPs), we propose core elements for ARVSPs that are based on published evidence, clinical experience, and adapted from antimicrobial stewardship programs.
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A Case of CNS Nocardia farcinica Presenting as Aphasia in an Immunocompetent HostQuick recognition is key to early initiation of treatment and long-term survival.
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Rocky Mountain Spotted Fever Risk Factors ExaminedThe survey of households found that although 80% of residents had heard of Rocky Mountain spotted fever, less than half used pesticides to prevent the presence of ticks.
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Individualized Beta-Lactam Therapy and MonitoringElevated beta-lactam concentrations have been associated with neurotoxic adverse effects, including seizures and mental status changes.
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Estimating HIV Screening Incidence Among US CitizensInvestigators used national electronic health record data to determine the proportion of American adults who have been tested for HIV.
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Coffee, Donuts, and Antimicrobial StewardshipTargeting stewardship interventions to the morning hours may have a greater impact than afternoons and nights.
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Systematic Review Highlights Hydroxychloroquine AmbiguitiesInvestigators sought to summarize evidence about the benefits and harms of hydroxychloroquine and chloroquine as treatments or prophylaxis of COVID-19.
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Guidelines to Caring for Patients With Sepsis: Promise or Progress?Care continues to improve; however, drug-resistant pathogens and a lack of new agents to treat these infections remain a constant challenge.
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Considerations for DischargeSakoulas offered his insights for when he considers discharging patients and strategies to avoid readmission.
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Teva Pharmaceuticals Announces Launch of Generic HIV DrugTeva Pharmaceuticals announces an exclusive launch of a generic version of atazanavir capsules for the treatment of HIV.
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Entering the Ring: Oral Vancomycin Versus Metronidazole for C difficile Infection and the Risk of Vancomycin-Resistant EnterococcusIn 2017, a guideline update stripped metronidazole of its first-line therapy designation and crowned oral vancomycin as initial therapy for all C difficile infection cases.
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Integrating Order Sets Into Antimicrobial Stewardship StrategiesSince its implementation in December 2016, use of a ceftolozane-tazobactam order set at Marin General Hospital has advanced antimicrobial stewardship efforts.
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Final Thoughts on COVID-19 and FluFinal thoughts from experts on controlling COVID-19 and influenza.
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Rapid ART Initiation: A New Model Presents Unique Opportunities and ChallengesPatients with a new diagnosis of HIV may benefit from rapid start of ART.
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Long-Acting Anti-MRSA Agents: One Dose to Cure?A review of the current literature and future directions.
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A Case of CNS Nocardia farcinica Presenting as Aphasia in an Immunocompetent HostQuick recognition is key to early initiation of treatment and long-term survival.
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Utilizing MRSA Nasal Screening for Antimicrobial StewardshipThis In the Literature piece details a study evaluating MRSA nasal screening’s effect on antimicrobial stewardship.
