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Eravacycline: The IGNITE Growth of the TetracyclinesThe synthetic novel tetracycline offers a new option for complicated intra-abdominal infections.
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Duration of Antibiotic Therapy for Uncomplicated Gram-Negative Bacteremia: Seven Is the New FourteenThe treatment duration for uncomplicated gram-negative bloodstream infections (BSIs) has traditionally ranged from 7 to 14 days. However, recent retrospective studies and meta-analyses have observed no differences in clinical outcomes in patients treated with shorter courses compared with prolonged courses, especially with urinary sources of infection.
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Reassessing Practices Is Critical During an Infectious Disease OutbreakThe constant reassessment of business practices is necessary to ensure that practitioners are not wasting valuable time, resources, and effort on activities that are not producing the desired results.
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Lessons From the MERINO TrialIs the use of piperacillin/tazobactam for bacteremia caused by ceftriaxone-nonsusceptible Escherichia coli and Klebsiella pneumoniae an obsolete practice?
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Tick, Tick, Tick: Vector-Borne Diseases Ramp UpInfections transmitted by these bloodsucking species are on the rise worldwide.
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Assessing Statin Use in HIV-Positive Patients Taking Protease InhibitorsA recent study takes a closer look at statin use in HIV-positive patients who are taking protease inhibitors.
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Sepsis and Antimicrobial Resistance Awareness Gain Ground, But Action Must ContinueAs antimicrobial therapies become less effective, more people are at risk for infections that can progress to sepsis.
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With the Opioid Epidemic, Communities See Dramatic Increases in Infectious DiseasesRising incidence of viral and bacterial infections has accompanied the opioid crisis, but it also presents new opportunities for multidisciplinary treatment and preventive care.
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“Triple Therapy” Facing Triple ThreatClinicians provide an overview of intraamniotic infections and offer treatment strategies for these challenging infections.
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A Long-Term Care Antimicrobial Stewardship Certificate Program for Pharmacists: Filling an Unmet NeedThis training will empower pharmacists practicing in LTC facilities to develop antimicrobial stewardship programs, improve patient outcomes related to infectious diseases, and facilitate compliance with CMS requirements.
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Intravenous Fosfomycin for Systemic Multidrug-Resistant InfectionsIntravenous (IV) fosfomycin offers a novel therapeutic option in the treatment of systemic multi-drug resistant (MDR) infections. Unanswered questions remain regarding its efficacy and specific role in our therapeutic arsenal.
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Thomas M. File, Jr., MD: COVID-19 Requires a Unified ApproachIn addition to providing important expertise into the management of this infection, our role in educating the public—in many cases providing an important perspective when fears tend to run high—is also essential.
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Never Ignore a New Rash in a Patient With AIDSA case of Kaposi sarcoma with immune reconstitution inflammatory syndrome.
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Bioaccumulation of Drugs by Human Gut Bacteria Can Affect Drug AvailabilityA new study demonstrated that gut organisms can alter drug availability by biotransformation on a significantly broader scale than previously expected.
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Pfizer's C. difficile Vaccine Succeeds in Phase II StudyResearchers found the experimental vaccine could potentially inhibit severe diarrhea and pseudomembranous colitis by inducing a functional antibody response that can neutralize the two main disease-causing toxins (toxin A or B) produced by C. difficile.
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Researchers Are Working on a Promising Novel Herpes VaccineAlbert Einstein College of Medicine researchers have developed a new vaccine type that shows promise to possibly become the first ever for preventing genital herpes.
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HIV Treatment Advice for Community PhysiciansExperts provide community physicians treating HIV with practical advice for screening, diagnosing, and managing patients with HIV.
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Have we made progress in the 10 X' 20 Initative?IDSA reached its goal, but nobody’s buying. Can the drowning antimicrobial pipeline be saved?
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Hepatitis C Virus: Task Shifting and ScreeningClinicians discuss screening and treatment approaches for the disease.
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Addressing Shortcomings in Infection and Sepsis Treatment Should Be Top of the Priority ListAs clinicians and health care executives work to strike a balance between reducing costs and improving clinical outcomes, the importance of sepsis identification and treatment cannot be underscored enough, and starts with evaluating current practices for infection management.
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The Public Health Threat of Ice Cream TamperingVideos of individuals licking ice cream and placing these cartons back on freezer store shelves have gone viral, and this practice can pose public health risks.
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Using IL-6 Inhibitors to Treat COVID-19Use of an IL-6 inhibitor has the potential to prevent the cytokine storm caused by severe COVID-19 infection.
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Genomic Features of the 2015 Elizabethkingia OutbreakResearchers from Pasteur Institute, Paris, France, and the Centers of Disease Control and Prevention, examine the genomic features of the E. anophelis strain behind the 2015-2016 Wisconsin outbreak.
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New Line of HIV Treatment Identified for Patients Ineligible for EfavirenzA national clinical trial has found non-efavirenz antiretroviral therapy effective as a first-line treatment, which is good news for patients with HIV who are ineligible to usea the common drug.
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COVID-19 Complicates an Already Difficult Presentation of Infective EndocarditisFinal Diagnosis: Infective Endocarditis Due to Granulicatella adiacens and Streptococcus mitis.
