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Tenofovir Plus Interferon Improves Antigen Clearance in Chronic Hepatitis BTreatment with a combination of tenofovir and pegylated interferon yielded higher rates of hepatitis B surface antigen (HBsAg) loss than when either drug was used singly. Further, with longer therapy duration improved results.
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Ocular Syphilis and Cytomegalovirus Retinitis Have Different Immunologic ProfilesResearchers have found that individuals with cytomegalovirus retinitis have a more advanced HIV infection than individuals with ocular syphilis.
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Decongestants and Hypertension: Dangerous TogetherPharmacists can play an important role in managing the use of these medications in patients, particularly those with high blood pressure.
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Five Ways ID Clinicians Can Take On Antibiotic Resistance: Highlights From the CDC's Latest ReportA death from an antibiotic-resistant infection occurs about every 15 minutes in the United States. The CDC’s 2019 threat report dives into national infection estimates and actions we can take to combat this threat.
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Gene Therapy Shows Promise in Neutralizing HIVResearchers safely infuse engineered immune cells in groundbreaking gene therapy study.
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Intraseasonal Influenza Vaccine Effectiveness Waning: Threading the Needle for ImmunityEvidence is accumulating that influenza vaccination protection wanes over the course of a single influenza season, with significant implications for public health.
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Gardnerella Bacteremia Reported in HIV-Positive MaleInvestigators from the University of California San Diego Medical School report on the first case of Gardnerella bacteremia in an HIV-positive male following the placement of a urinary catheter.
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Letters to Doctors Help Fight Over-Prescription of AntibioticsA new trial conducted in England has discovered a cost-effective way to reduce the overprescribing of antibiotics by general practitioners (GPs).
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Controversies of Antimicrobial Transitions in Adults With Gram-Negative BacteremiaMoving away from the standard course of IV antibiotics.
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What the 2018 DRC Ebola Epidemic Taught Us About Outbreak Response and Experimental CountermeasuresHow has treating infections changed with the availability of experimental vaccines and therapeutics, and how can we apply this to COVID-19 today?
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A Case of Chronic Granulomatous Mastitis Caused by Corynebacterium kroppenstedtiiA full case study from our August 2020 issue.
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An Unknown Contagious Rash: Case Report and Literature Review of Norwegian Crusted ScabiesA patient with HIV and skin lesions should trigger a broad differential.
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Current and Potential Treatment Options for Stenotrophomonas maltophilia InfectionsWe review current and emerging treatment options for infections caused by the difficult-to-treat, intrinsically multidrug-resistant organism Stenotrophomonas maltophilia.
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An Unusual Case of Testicular Swelling in a Patient With HIVBeing immunocompromised increases risk of rare Mycobacterium tuberculosis epididymo-orchitis.
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Community Acquired Pneumonia and the Role of Adjunctive CorticosteroidsAntibiotics are the mainstay treatment for CAP; however, the additive role of corticosteroids is continually being debated.
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Cryptosporidium: A Potentially Fatal Cause of Diarrhea in a Heart Transplant RecipientExpanding the differential for diarrhea beyond Clostridium difficile.
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Evidence-Based Intervention Reduces C. diff Rates in Adults With CancerSMUCLA implements high-touch wipe down intervention to address the need for environmental disinfection of cancer patient care areas.
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Are Two Antibiotics Better Than One?A commentary on β-lactam combination therapy for methicillin-resistant Staphylococcus aureus bacteremia.
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The Ripple Effect of Climate Change on Epidemic RiskWhile rising temperatures and sea levels are often considered, changing climate patterns can have vast implications for epidemic risk as well.
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Five Ways ID Clinicians Can Take On Antibiotic Resistance: Highlights From the CDC's Latest ReportA death from an antibiotic-resistant infection occurs about every 15 minutes in the United States. The CDC’s 2019 threat report dives into national infection estimates and actions we can take to combat this threat.
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A Case of Disseminated Nocardia farcinica Presenting as Fever of Unknown Origin in a Transplant PatientOutcomes in disseminated nocardiosis are variable and depend on patient factors.
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Four Fungal Horsemen: Emerging Trends in Fungal Disease EpidemiologyNew public health perspectives on aspergillosis, sporotrichosis, histoplasmosis, and coccidioidomycosis.
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Long-Acting Anti-MRSA Agents: One Dose to Cure?A review of the current literature and future directions.
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New Technology Enables Differentiation of Bacterial and Viral InfectionsIt can help inform appropriate antibiotic prescribing, but likely would only form part of testing protocol, experts say.
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Living and Aging With HIV: Recognition and Management of Common Prescribing PitfallsWith advancements in antiretroviral therapy, people with HIV are now living longer and developing age-related chronic conditions.
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An Unknown Contagious Rash: Case Report and Literature Review of Norwegian Crusted ScabiesA patient with HIV and skin lesions should trigger a broad differential.
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With the Opioid Epidemic, Communities See Dramatic Increases in Infectious DiseasesRising incidence of viral and bacterial infections has accompanied the opioid crisis, but it also presents new opportunities for multidisciplinary treatment and preventive care.
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Antibiotic Stewardship Programs in the Hospital Setting: Guidance from the Centers for Disease Control and PreventionWhile antibiotics serve a meaningful purpose in treating infections, appropriate use of these agents is needed in order to minimize adverse events.
