HCV / Hepatitis

In a study presented at CROI 2017 in Seattle, Washington, researchers from MedStar Health Research Institute presented new data on HCV infection in non-baby boomer populations.

Research presented at the recent Conference on Retroviruses and Opportunistic Infections shows that more individuals are aware of their HIV and hepatitis C (HCV) status, but more work is still needed.

Researchers presented their findings on pre-seroconversion window in patients with acute HCV infection at the Conference on Retrovirus and Opportunistic Infections in Seattle, Washington.

Researchers found that HCV infection may be linked to more cancers besides hepatocellular carcinoma, as well as certain types of non-Hodgkin lymphoma.

In a recent CHeCS study, investigators sought to identify the prevalence of cirrhosis, decompensated cirrhosis, and death, among 11,169 adults with HCV in the United States between 2006 and 2014.

A retrospective study found hepatitis C reinfection rates high are in HIV-positive men who have sex with men from four western European countries.

A recent study from US researchers suggests that liver disease severity and treatment costs for people with hepatitis C (HCV) vary depending on a patient’s genotype.

Regulus Therapeutic’s hepatitis C drug, RG-101, has been on clinical hold since mid-2016; FDA calls for additional data before hold is lifted.

Megan Luther, PharmD, Advanced Health Services research fellow, Providence Veterans Affairs Medical Center, University of Rhode Island, College of Pharmacy, discusses potential strategies to reduce incidence of acute kidney injuries due to vancomycin and pip/tazo combination therapy.

The retrospective study included a cohort of patients from six countries across Europe who were diagnosed with HCV and received daclatasvir during the Named Patient Program.

A new study finds that cancer incidence in individuals with cirrhosis is lower than originally believed—at most, about 4%.

According to the Belgian researchers, Sofosbuvir in combination with simeprevir with or without ribarivirn was found to be well-tolerated and efficacious.

In a review article published in Rheumatic Disease Clinics of North America, researchers discuss the main rheumatologic diseases associated with chronic HCV infection, and how DAAs have affected these extrahepatic manifestations.

Monique Foster, MD, MPH, EIS officer, Division of Viral Hepatitis, Centers for Disease Control and Prevention (CDC), discusses the CDC’s HCV universal birth cohort testing program.

A research group from Hokkaido University in Japan found that standard treatment for those with genotype 1 HCV should likely be switched from interferon (INF)-based therapies to INF-free direct-acting antiviral (DAA) therapies.

A report warns that liver failure might be associated with nine new direct-acting antivirals (DAA).

A group of researchers recently published a study in JAMA, examining conflicts of interest (COIs) among committee members who set hepatitis C (HCV) and cholesterol management guidelines. They found that there, in fact, were COIs among committee members setting HCV management guidelines.

The European Medicines Agency has fully validated Gilead’s SOf/VEL/VOX regimen to treat hepatitis C (HCV).

Monique Foster, MD, MPH, EIS officer, Division of Viral Hepatitis, Centers for Disease Control and Prevention, explains that hepatitis C infection awareness has been on the rise in the United States.

Felix Kleefeld, of Berlin, Germany, and colleagues examined how eradicating HCV affected the cognition of patients in a study published in Neurology in December 2016.

Researchers conducted a post hoc analysis to learn whether or not the length of time it took to attain initial viral suppression is related to sustained virologic response (SVR) rates for patients receiving the so-call 3D treatment, with or without ribavirin.

Insurance companies are denying members coverage to expensive drugs, like Harvoni, and those infected with HCV are filing lawsuits.

Monique Foster, MD, MPH, EIS officer, Division of Viral Hepatitis, Centers for Disease Control and Prevention, discusses the importance of new medications to treat hepatitis C.

A new project aims to develop and assess new hepatitis C vaccination strategies in an effort to improve treatment.

Researchers offer more insight on the role of IFN-I and find a potential therapeutic target that may be able to protect against chronic viral infections.