Targeted Prophylaxis Reduces Hospital-Onset C difficile Infections in High-Risk Patients
October 22nd 2024The STOP-CDI intervention presented by Matthew J.Ziegler, MD MSCE revealed using prophylactic enteral vancomycin, significantly reduced hospital-onset C difficile infections among immunocompromised patients.
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Evaluating the Efficacy of Paxlovid in High-Risk Patients with Pre-Existing Immunity
October 22nd 2024John McLaughlin, PhD, examines high-risk individuals with prior SARS-CoV-2 immunity and presents that Paxlovid reduces the risk of hospitalization, death, and severe symptoms, highlighting its ongoing value for high-risk patients in a post-peak pandemic landscape.
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A Monoclonal Antibodies' Prospective Place in the COVID-19 PrEP Market
October 21st 2024Invivyd’s Chief Scientific Officer Robert Allen, PhD, discusses the company’s pemivibart (Pemgarda) including its administration, how it can be used in concert with vaccines, and how it protects against newer variants.
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Long-Acting Injectable HIV Therapy: Addressing Adherence Challenges
October 21st 2024Elizabeth Hastie, MD discussed the LATITUDE trial results, highlighting the need for wider access to this treatment, especially for those not virally suppressed, and could help shape future healthcare guidelines.
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Long COVID’s Impact on the Brain, Specifically Cognitive Function
In our latest roundtable series, experts highlighted research showing that even mild COVID can result in cognitive impairment including brain fog and IQ decline.
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Getting Patients Involved in C diff Advocacy, Treatment Guidelines
October 18th 2024Peggy Lillis Foundation CEO Christian Lillis believes patients need a seat at the table so he is advocating for past patients to become ambassadors to be a voice to help shape treatment and also continue to raise awareness about the infection.
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Analyzing Household Transmission of COVID-19
October 17th 2024At ID Week 2024, an investigator, Amanda M. Casto, MD, PhD, discusses her work on the CASCADIA study, which examined infection rates in this setting, and how it challenged assumptions that there is likely a singular carrier bringing viruses into homes.
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Enhancing Outcomes in Outpatient Parenteral Antimicrobial Therapy
October 17th 2024Nabin K. Shrestha, MD, MPH, evaluates the Cleveland Clinic's Outpatient Parenteral Antimicrobial Therapy (OPAT) program, revealing its effectiveness in managing infections while highlighting challenges in monitoring and the impact of infectious disease pharmacists on patient outcomes.
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Kalihinol Analog Targets Apicoplast Function In Malaria Treatment
October 17th 2024Karine G. Le Roch, PhD, discussed her research on a kalihinol analog that combats drug resistance in malaria, emphasizing the need for innovative treatments in the context of climate change and rising transmission rates.
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Gilead's Phase 1a Trial Results Indicate GS-1720 as a Potential Long-Acting HIV Treatment
October 16th 2024GS-1720 could offer a weekly dosing option for individuals living with HIV, supported by a good safety profile with no serious adverse events, which has led to the initiation of a Phase 2 study.
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Further Data Finds Lenacapavir to Be Safe and Tolerable for PrEP Use
Published: October 15th 2024 | Updated: October 15th 2024The Gilead capsid inhibitor has been shown to have less adverse events compared to another PrEP, and the company plans to begin regulatory filings for approval before the end of this year.
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Unmasking Long COVID Through Understanding Prevalence and Diagnosis
In our latest roundtable series, the discussion addressed Long COVID prevalence, underreporting, accurate diagnosis, and emphasized that Long COVID serves as an umbrella term.
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Diagnostic Stewardship, Data Collection, and Incentives are Themes of UN General Assembly on AMR
October 10th 2024A holistic, multifaceted approach with a variety of stakeholders are needed to address antimicrobial resistance (AMR). The recent UN meeting on this topic looked to bring together government leaders, industry, and public health officials to discuss strategies regarding the global health crisis.
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GigaGen's New Contract with BARDA for Polyclonal Antibody Development
October 4th 2024Carter Keller discusses the company's recent $135.2 million contract with BARDA to develop recombinant polyclonal antibody therapies targeting botulinum neurotoxins and an unspecified biothreat, highlighting their innovative approach to address emerging health threats.
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Evaluating Safety and Efficacy of Vaxart's Oral Vaccine's Impact on COVID-19 Variants
October 4th 2024Part 2 with James F Cummings, MD, as he discusses the need for a stronger response to emerging variants, the importance of protecting high-risk populations, and the potential to reduce vaccine hesitancy through easier administration.
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Advocating for Better Regulatory Rules and Standard of Care for C difficile
September 25th 2024Maryann Webb’s harrowing, personal experience with C diff, along with her professional work with federal agencies has prepared her for a life in advocacy with the Peggy Lillis Foundation. She wants to see the fecal microbiota transplant become more accessible and is working with Congress to make the infection a notifiable infectious disease.
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A Novel Approach to Infectious Disease Surveillance
September 16th 2024The International Society for Infectious Diseases (ISID) ProMED surveillance system is a way for clinicians and interested ID stakeholders to be aware of local outbreaks and follow-up in response to get more information on them.
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