This Week's Top Five Infectious Disease Stories
July 22nd 2023Coverage this week included how COVID-19 vaccines in patients with cancer fared; analysis of non-COVID-19 adult vaccines; a company is developing a platform to enable engineering of the first recombinant human polyclonal antibody therapies with the goal of creating a functional cure for hepatitis b; and how a hospital modified testing for C difficile.
2-Step Testing Helps Predict and Treat Recurrent C difficile Infection
July 19th 2023This study explores the effectiveness of PCR and toxin EIA testing in predicting C difficile infection (CDI) outcomes. The research reveals that patients with negative toxin results were less likely to experience CDI recurrence within 30 days.
Largest Safety Evaluation of Microbiota-Based Therapeutic Reveals Rebyota's Positive Profile
July 18th 2023Rebyota, the first FDA-approved microbiota-based live biotherapeutic for preventing recurrent Clostridioides difficile infection (rCDI), has been the subject of a groundbreaking safety analysis.
COVID-19's Impact on Alzheimer's: Uncovering 2 Years of Mortality Trends
July 17th 2023This study found a substantial increase in Alzheimer's-related deaths during the initial year of the pandemic due to limited access to healthcare, social isolation, and disrupted care routines. However, the second year brought positive developments with prevention strategies and vaccinations, leading to a substantial decline in excess deaths.
Investigational C diff Antibody Takes Novel Mechanism of Action Approach
July 14th 2023Lumen Bioscience's C diff therapy, LMN-201, combines four therapeutic proteins that act synergistically to neutralize both the C difficile bacterium and the toxin that causes its virulence directly in the patient’s gastrointestinal tract.
COVID-19 Vaccines Bridge Socioeconomic Disparities in Pandemic Impact, CDC Study Shows
July 13th 2023This study analyzed 81 communities in Los Angeles and found that once vaccines became widely available, there was no significant difference in COVID-19 incidence between communities of varying income levels.
Antimicrobial Resistance Emerges More Quickly in Mixed Strain Bacterial Infections
July 12th 2023A new study finds antimicrobial resistance (AMR) evolves rapidly in patients colonized by diverse P aeruginosa populations due to selection for preexisting resistant strains, demonstrating a clear link between within-host diversity and resistance.