Health Care Worker Seroprevalence Data Show Undetected COVID-19 Spread
A new CDC Morbidity and Mortality Weekly Report adds information on seroprevalence of SARS-CoV-2 among health care workers in a 13-hospital multistate medical network between April and June of 2020.
Comparing Asthma Complications in COVID-19 With Flu
A study team examined asthma prevalence in patients hospitalized for COVID-19 with population asthma prevalence and a 4-year average of asthma prevalence in influenza hospitalizations across the United States.
Relation of SARS-CoV-2 Reinfection to Cellular Immunity
John F. Kokai-Kun, PhD, Director of External Scientific Collaboration at USP, discusses the recent report of SARS-CoV-2 reinfection.
Antimicrobial Use in COVID-19 Patients
Are COVID-19 patients getting early empiric antibiotics?
Modeling Predicts Contact Tracing Can Contain COVID-19 Despite Relaxed Distancing Measures
Mathematical modeling for tracing COVID-19 contacts can account for likely scenarios of inconsistent physical distancing and quarantine adherence
Analysis Suggests Scope of COVID-19 Outbreak in US Was Underestimated in Early Days
An estimate that 100K may have been infected by mid-March dwarfs official figures.
Plasma Transfusion for COVID-19 Explained
John F. Kokai-Kun, PhD, Director of External Scientific Collaboration at US Pharmacopeia, explains the fundamentals of convalescent plasma treatment for COVID-19.
Raj Bhopal Full Interview: COVID-19 Zugzwang
Bhopal’s recent article, COVID-19 Zugzwang, was published in Public Health in Practice.
FDA Pipeline: EUA Granted for Plasma, Remdesivir Expands to Moderate Cases
A refresher on the week's developments in the infectious disease drug & medical device FDA approval pipeline.
Sanitizer Recalls Expanded Due to 1-Propanol
The FDA regularly posts updates on recalls, outbreak investigations, and related regulatory activities. Weekly, we identify which of those announcements might be most clinically relevant.
Remdesivir Receives EUA for Patients With Moderate COVID-19
FDA expands usage to all hospitalized COVID-19 patients.
US Purchases 150 Million COVID-19 Antigen Tests from Abbott
The 15-minute test was granted emergency authorization by the FDA earlier this week.
Monoclonal Antibody Research: Supply Chain Issues
John F. Kokai-Kun, PhD, explains the supply chain and logistical issues limiting the scale of monoclonal antibody treatment.
What are Monoclonal Antibodies [mAb]? | John F. Kokai Kun, PhD
John F. Kokai-Kun, PhD, Director of External Scientific Collaboration at US Pharmacopeia, explains the fundamentals of monoclonal antibody treatment.
Report Recommends Personalized Approach to Treating Sepsis
A new report suggests a personalized approach to sepsis treatment, recommending prompt antimicrobial therapy for the sickest patients and a more personalize approach for those with less severe cases.
Remdesivir Designation as Orphan Drug Exposed Policy Loophole
The short-lived designation of remdesivir as an Orphan Drug to treat COVID-19 exposed loophole in the Orphan Drug Act.
Covid-19 and Paralysis of the Immune System
How can critically ill COVID-19 patients experience immune system “paralysis” when inflammatory processes are in overdrive?
Did COVID-19 Fears Lead to Fewer Stroke Admissions?
Hospital admissions for stroke fell by nearly a third during March and April 2020 alone when compared with those months in 2019.
Comparing N95 Respirator Mask Decontamination Methods
A study team assessed 4 methods of N95 mask decontamination, with results suggesting that proper procedure can allow the reuse of masks 2-3 times.
Can Masks Replace Social Distancing?
Martin Kulldorff, PhD, explains that masks can't replace social distancing for those at highest risk for severe COVID-19.
Acute Cellulitis: Meta-Analysis Does Not Reveal Optimal Antibiotic Regimen
A systematic review and meta-analysis was undertaken to ascertain optimal route and duration of antibiotic treatment of acute cellulitis
Commentary Suggests That Remdesivir Should Only Be the Beginning
Drug has shown promise in COVID-19, but other, oral options are needed.
FDA Approves 15-Minute COVID-19 Antigen Test
The device has test result features likened to pregnancy tests, and can be produced vastly every month.
COVID-19 Is Not Driving Better Healthcare Discussion
Brad Spellberg, MD, explains how real progress can be made to a debted system with worsened rates of user health.
How COVID-19 Response Impacted Essential Workers
Martin Kulldorff, PhD, answers whether an age based coronavirus strategy would worsen the pandemic's impact on workers and minority racial groups.
COVID-19 Vaccine Candidate mRNA-1273 Reports Interim Phase 1 Data
Investigators report comparable SARS-CoV-2 neutralizing antibody counts across age groups, as well as favorable safety outcomes for the two-dose vaccine.
COVID-19 Hospital Data Reveal Rush to Antibiotics
Soon after visiting 38 hospitals in Michigan, over half of patients hospitalized with suspected COVID-19 received antibiotics.
CDC Refines COVID-19 Travel Guidance, Quarantine Recommendations
The US Centers for Disease Control and Prevention has updated COVID-19 guidance, sharing advice on safe travel
Wild Polio is Declared Eradicated from Africa
ARCC made the announcement yesterday that the WHO African Region is free of the virus.
Antiretroviral Shows to be Safe for Newly Diagnosed Adults with HIV
ViiV Healthcare’s dolutegravir/lamivudine (Dovato) may be potential treatment option for this patient population