BRAAVE 2020: Biktarvy Noninferior as a Switch Treatment for Black Americans Living With HIV
The results support B/F/TAF as a switch option for Black Americans who are virologically suppressed, including individuals with a history of treatment failure or pre-existing resistance.
COVID-19’s Effect on Clinical Trials of Long-Acting Cabotegravir and Rilpivirine for HIV Infection
How has the COVID-19 pandemic affected clinical trial site restrictions, drug delivery, dosing, patient monitoring, and follow-up?
SARS-CoV-2 Household Transmission Risk is Significantly High
New data presented at IDWeek showed more than half observed households with a COVID-19 case reported a secondary infection, oftentimes within 3 days.
Intravenous Immunoglobulin Beneficial for Severe COVID-19
Phase 1 data and a history of benefit for worsening respiratory infections show promise for the therapy.
Tri-Antigenic Hepatitis B Vaccine Elicits Significant Immunity
New head-to-head phase 3 data show a promising potential new HBV vaccine may join the market in the near future.
Asymptomatic and Symptomatic COVID-19 Nursing Home Residents: Who Carries the Greater Viral Load?
In a large nursing home study, asymptomatic and symptomatic residents were found to carry similar viral loads.
Oral Care May Prevent Hospital-Acquired Pneumonia Spread
New data show ADA-recommended oral care for inpatients is associated with an 85% reduction in NVHAP infections at an 800-bed medical center over a year.
Weight Changes When Switching PWH from ABC or TDF to TAF
A study looked at weight gain when changing therapy regimens.
AstraZeneca COVID-19 Vaccine Volunteer Dies
The participant was taking a placebo and the trial will continue according to initial reports.
SURE-1 Trial: Results of Sulopenem Vs Ciprofloxacin
Sulopenem was superior to ciprofloxacin for the treatment of uncomplicated urinary tract infections.
Investigational RSV Vaccine Found to be Immunogenic
In a phase 1/2 randomized clinical trial, GlaxoSmithKline’s RSVPreF3 vaccine elicits a response.
DAV132, Novel Colon-Targeted Adsorbent, Protects Intestinal Microbiota From Antibiotic-Induced Dysbiosis
The composition of the gut microbiome is easily disrupted by antibiotics, leaving the host susceptible to further infection or other disturbance of gut flora that can lead to both short- and long-term deleterious effects.
Vaccine Race: Mei Mei Hu on Developing, Researching a COVID-19 Vaccine
A vaccine developer joins for a firsthand discussion on the development, research, and distribution process.
How the COVID-19 Pandemic Has Affected Physician Economic Burden and Workload
In results of a national survey, investigators pieced together a look at the psychological toll of the pandemic on physicians and identified the biggest stressors.
CovidIQ Text Tool Successfully Predicts COVID-19 Hot Spots Before Agencies
The CovidIQ tool successfully predicted a COVID-19 spike in Jacksonville, Florida, a full 2 weeks before it was recognized by the Florida Department of Health.
ALLIUM Trial: Cefepime-Enmetazobactam Superior to Piperacillin-Tazobactam for ESBL-Producing Enterobacterales
Antimicrobial-resistant infections, in particular those caused by gram-negative pathogens that also produce extended spectrum β-lactamases (ESBL), represent a growing threat across the globe as investigators race to develop novel therapeutics
What’s New in 2020 From the CLSI Subcommittee on Antimicrobial Susceptibility Testing
Benefits of ID Consultation and ASP Collaboration
How COVID-19 Influences Allergies, Neurology, and Sleep
A summary of new studies surrounding COVID-19 comorbid effects.
Remdesivir Fails to Benefit COVID-19 Hospitalization, Death in WHO Study
After a series of positive developments, the antiviral agent joins a quartet of candidates that failed to improve severely ill COVID-19 status in the Solidarity study.
Pfizer, BioNTech COVID-19 Vaccine Planned for Late November FDA Submission
Pfizer anticipates to have completed FDA-mandated safety data a month from now. An EUA application should shortly follow.
When Shorter May Not Be Better: Pseudomonas Infection in Hematopoietic Stem Cell Transplant Recipients
FDA Approves First Ebola Virus Treatment
US Reports First Confirmed COVID-19 Reinfection Patient
A 25-year-old male in Nevada was hospitalized due to a different SARS-CoV-2 strain 2 months after recovering from a first case.
Partners in antimicrobial crime: Vancomycin and daptomycin in combination with β-lactams for serious MRSA infections
COVID-19 Vaccine Race: Donald Alcendor, PhD, on Community Buy-In
The Meharry and Vanderbilt-based expert shares insights into reaching less trustful populations on the first podcast episode.
COVID-19 and Understanding Immunity
Fundamental aspects of immunity to SARS-CoV-2 remain elusive. Here is an examination of some potential clues to protection.
How COVID-19 May Affect the Future
A collection of expert perspectives on what the virus itself may mean for future crises.
Remdesivir Plus Baricitinib Reduces Hospitalized COVID-19 Mortality by 35%
New ACTT-2 data shows a marked benefit from the combination regimen versus lone remdesivir.
Remdesivir Linked to Five-Day Reduction in COVID-19 Hospital Stay
ACTT-1 findings for the Gilead antiviral show it improved chance of clinical improvement by 50% in very ill COVID-19 patients.
