IDSA Guidance on the Treatment of Antimicrobial Resistant Gram-Negative Infections
Since late 2004, 7 novel antibiotics with activity against ESBL-E, CRE, and/or DTR P aeruginosa have been approved.
Mothers with COVID-19 Can Safely Room-in with Newborns
A new study from Italy provides evidence that new mothers with COVID-19 can safely breastfeed and stay together in the same room with their newborns after delivery if they follow safety precautions.
Novel Salvage Therapy for Multidrug-Resistant HIV Infection
First Inactivated COVID-19 Vaccine in European Union Goes into Clinical Trial
Vaccine manufacturer Valneva recently announced it was initiating a phase 1/2 trial in the United Kingdom.
Promising Mini Antibodies Against COVID-19 Isolated
Anti-COVID-19 nanobodies may potentially be effective at preventing and diagnosing infections.
NIH Sponsored ACTIV-3 Trial Results Published
Phase 3 trial data shows experimental monoclonal antibody not to be efficacious.
Understanding why COVID-19 Increases Stroke Risk
While ACE2 expression has been reported in the human brain, the cell-specific expression pattern of ACE2 is unknown.
C. Difficile: Are We Making Progress?
Pfizer Nearing Increased COVID-19 Vaccine Deal with the US
The agreement could mean upwards of 70 million more doses for eligible patients in mid-2021.
How Coronavirus Interacts with Cells
Characterizing SARS-CoV-2 interactions can improve understanding of viral RNA functions and the host innate immune response.
Model Shows Benefits and Drawbacks of COVID-19 Pool Testing
Regional and national decision-making can be informed by the online model, called the COVID-19 Pool Tool.
BioNTech Executive Expresses Hope for Vaccine Versus New COVID-19 Strain
Though research is pending, the CEO used simple science to explain why the mRNA vaccine may still prevent from the UK variant.
Most Realistic Snapshot of Coronavirus Spike Protein Structure Viewed
The study helps to illuminate how spike proteins initiate infections.
Fostemsavir for Multidrug Resistant HIV-1: It’s Time for HIV to Overcome Attachment Issues With CD4 Cells
Fostemsavir, an HIV-1 attachment inhibitor, is a novel therapeutic option for multidrug-resistant HIV. It represents the first oral agent developed for this indication in over a decade and provides promise for patients with limited remaining treatment options.
Treatment for Ebola Virus Approved by FDA
An Orphan Drug Designation was granted to Ridgeback Biotherapeutics, LP, creator the therapy.
New COVID-19 Variant Circling the UK
Countries across Europe are reinstating travel bans and lockdowns to combat virus.
How SARS-CoV-2 Is Presenting in Infants
A new case series report highlights the unique circumstances of infant illness associated with COVID-19.
Afabicin: A Novel, Narrow-Spectrum, Antistaphylococcal Agent
The Case for Pooled SARS-CoV-2 Testing
New data suggests informed, practical pooled testing could improve both public health response and clinical assessment of the pandemic.
Entering the Phase of Phage: A Closer Look at Bacteriophage Therapy
Greatest Risk Factors of Mortality from COVID-19
Healthcare providers may want to consider these risks when determining which COVID-19 patients could benefit the most from the new monoclonal antibody therapies.
Emergency Use Authorizations for COVID-19 Therapeutics: The Good, the Bad, and the Data-Deficient
FDA Authorizes Moderna’s COVID-19 Vaccine in the US
The VRBPAC voted 20-0 with 1 abstention to support the benefit-risk profile associated with mRNA-1273.
CDC Updates Treatment Guidelines for Gonococcal Infection
The CDC stressed that antimicrobial stewardship remains a major public health concern.
COVID-19 Found to Cause More Severe Disease than Seasonal Influenza
The authors note that the difference in hospitalization rate may be partly due to existing immunity to influenza in the population.
Sporadic Pediatric Norovirus Cases May Predict Broader Outbreaks
Investigators in Tennessee detailed associations between seasonal increases in sporadic pediatric cases of norovirus gastroenteritis and reported norovirus outbreaks among older populations.
Finding a Role for Remdesivir as Part of Combo Therapy for COVID-19
Regimen reduces mortality and recovery time in patients severely ill with pneumonia caused by the virus.
Holiday Guest List—When the Uninvited Arrive: COVID-19 and Coinfections
FDA Advisory Committee Votes to Support EUA for Moderna's COVID-19 Vaccine
At the interim analysis, the mRNA-1273 vaccine was found to have an efficacy of 94.5% against confirmed COVID-19.
Pregnant Women Excluded From Three-Quarters of COVID-19 Trials
Review of data in trial registries shows they specifically excluded this group from studies involving therapies.
