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The healthcare sector currently faces an unmet need in treating herpesviruses, hepatitis B, and hepatitis D, which could significantly improve patient outcomes. Addressing this involves considering the necessary steps and understanding the challenges pharmaceutical companies encounter as they work towards developing treatments for these conditions.

Colorado man infected with avian influenza, Novavax reveals promising results in JN1 covid vaccine efficacy, and recent roundups of c difficile news, and more from Contagion.

The $176 million award is for late-stage development of widespread immunization capability against H5 (avian) influenza, should such vaccines be needed.

The case occurred to a man in Colorado who had direct contact with cattle and state public health officials offer details on the patient as well as the risk to the public.

Boosted neutralization against variant XBB15 fades within 3 months post-first booster in transplant recipients but improves with a second, hybrid immunity enhances, suggesting 3-6 month boost intervals for solid organ transplant recipients.

Recent studies in Emerging Infectious Diseases have highlighted the persistence of highly pathogenic avian influenza A (H5N1) virus on milking equipment surfaces and its presence in dairy cattle mammary glands.

A new study demonstrates that the continuous infusion of β-lactam antibiotics could offer better clinical outcomes in treating sepsis, despite the nuanced statistical results.

Meta-analysis revealing higher 90-day mortality with intermittent than continuous infusion of ß-lactams for sepsis prompts call for latter to be standard of care.

Enjoy a healthy and memorable 4th of July by prioritizing food safety while savoring delicious meals with family and friends.

In the latest Bench to Bedside column, clinicians provide information and resources on recommended topics learners should explore.

Novavax, Inc has unveiled promising results regarding its JN1 COVID-19 vaccine's efficacy against emerging virus variants, including KP2 and KP3.

Biosurveillance has evolved beyond biodefense, emphasizing a comprehensive network to detect and counter biological threats.

A new study shows a greater likelihood of contracting this foodborne illness associated with a local area's socioeconomic vulnerability index (SVI) rank level, and reinforces the importance of addressing disparities in food safety.

Focused on microbial dynamics and inflammatory markers during remission, the study reveals persistent dysbiosis in the small intestine despite clinical improvements.

DDW 2024 highlighted advances in managing recurrent C difficile infections, emphasis on the effectiveness of live biotherapeutic products and the impact of antibiotic stewardship, and more ongoing efforts in combating C difficile.

Biopharmaceutical company, Dynavax, is comparing its investigational immunization against a FDA-approved vaccine.

The FDA recalls ice cream, orzo, and mixed nuts. Also this week, interviews with Jared Baeten, MD, PhD, on Lenacapavir's 100% efficacy against HIV, and Jason Roberts, PhD, on the promise of continuous β-Lactam against sepsis, and more from Contagion.

During today's CDC Advisory Committee on Immunization Practices (ACIP) meeting, committee members voted to recommend the FDA-authorized 2024-2025 COVID-19 vaccines for individuals aged 6 months and older. Additionally, they reaffirmed the existing influenza vaccination guidelines for the 2024-2025 season.

The test was validated as part of the NIH’s RADx tech program through its Independent Test Assessment Program, in collaboration with the FDA.

A Florida hospital takes a novel approach for the healthcare-associated infection and reduced inappropriate testing by setting up guidelines.

The federal agency says everyone 75 years of age and older should receive the RSV vaccine.

Jared Baeten, MD, PhD emphasizes the importance of the innovative PURPOSE 1 study in the fight against HIV, coinciding with National HIV Testing Day, today serves as a reminder of the ongoing efforts to expand testing access and develop new tools to combat HIV globally.

A retracted paper that erroneously claimed the measles, mumps and rubella (MMR) vaccine caused autism has repercussions still being felt today around topics such as vaccination, misinformation and disinformation, and measles incidence rates.

A case study of an 80-year-old patient, illustrating successful management of dual H pylori and C diff infections with quadruple therapy, with key insights from Yazan Abboud, MD and Sima Vossough-Teehan, MD.

The WHO reports the variant, clade I MPXV, has been circulating in a region within the Democratic Republic of Congo since last year.

Updates from June 24, 2024, on FDA-issued food recalls highlight potential issues such as Listeria contamination, mold growth, and undeclared allergens.

Findings from a pair of phase 2a trials showed combination imdusiran and IFN or VTP-300 with standard-of-care NA therapy led to meaningful and sustained reductions in HBsAg levels.

The study analyzed over 15 years shows declining rates of chronic and acute Hepatitis B in China, which is expected to make a significant contribution to the global elimination of hepatitis B by 2030.

Those individuals who received older versions of vaccines did not see significantly reduced risks of severe COVID-19 outcomes.

Researchers assess the efficacy of fecal microbiota transplantation (FMT) for first or second episodes of Cdifficile infection (CDI), demonstrating high initial cure rates and sustained in managing the condition.