Overdose Deaths Encroach on Life Expectancy Gains Among People Living With HIV
Experts assessed the impact of drug overdoses on people living with HIV in British Columbia, identifying factors associated with mortality using competing risk methodology.
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Money, Pills, and Isolation: Survey Reveals Concerns of Aging Patients With HIV
People with HIV are living longer than ever at present time, raising quality of life concerns about later stage medical and psychological challenges comorbidities.
COVID-19 Mortality Rates and Outcomes for HIV Patients Better Than HIV-Negative Group
Small study shows HIV patients not at a greater risk for worse outcomes.
California PrEP Push Reveals Underserved Demographics
The California PrEP Assistance Program, established to remove financial and structural barriers to PrEP access, had positive but uneven initial results.
The Burden of Multidrug-Resistant HIV
With fostemsavir now available for patients with few options, an expert discusses what challenges MDR-HIV patients face in their care.
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Urine HIV Self-Testing in China Shows Effectiveness
With insufficient HIV diagnosis testing in that country, this novel testing could help it reach part of its UNAIDS 90-90-90 targets.
First Possible HIV Remission Case without Bone Marrow Transplant Observed
A 34-year-old Brazilian man's HIV was undetectable 57 weeks after ending a heightened regimen of ART.
Fostemsavir Benefits Multi-Drug Resistant HIV
A look at the BRIGHTE study data which evidenced the recently FDA-approved add-on agent.
Switching to Second-Line Therapy Versus First-Line Antiretroviral
In low-level HIV-1 viraemia patients, this strategy demonstrated viral suppression in more than half of a study's participants.
Survey: Two-Thirds of US Adults Have Not Received HIV Testing
Despite being recommended at least once among all persons aged 13-64 years old by the CDC, notably few respondents have ever been tested for HIV.
Combatting Virologic Failure in Children with HIV using Targeted Drug Resistance Testing
Guidelines recommend concentrated adherence counseling and frequent viral load testing for virologic failure, but drug resistance testing is often excluded.
Eight-Week Cabotegravir Injection Has HIV PrEP Potential
Interim analysis shows a long-acting injectable was associated with fewer HIV infections than daily oral PrEP in a diverse population of HIV-risk participants.
Doravirine Benefits HIV-1 Patients with Common RAMs
A retrospective analysis of the DRIVE-FORWARD and DRIVE-AHEAD trials shows treatment-naive patients particularly fared well from the novel agent.
Gaining Insights into Islatravir and Doravirine
Carey Hwang, MD, PhD, executive director and product development lead, Global Clinical Development of Infectious Disease at Merck spoke with Contagion® regarding the therapies and went further into depth about the studies.
UNAIDS Report: Inequality and Coronavirus Risk a Decade of HIV Progress
A report released for AIDS 2020 warns the international AIDS response could be set back substantially by ongoing events.
Clinics Test Long-Acting HIV Therapy Implementation Strategies in Cabotegravir-Rilpivirine Trial
CUSTOMIZE was designed to identify methods of implementing an experimental once-monthly, long-acting regimen antiretroviral therapy against HIV-1 into clinical practice.
Eravacycline Realizes Successful Clinical Endpoint in OPAT Facilities
The antibacterial is efficacious in a majority of patients in a small study.
Antibiotic Scorecards Lead to More Appropriate Prescribing
Antimicrobial stewardship education was conducted with de-identified provider-specific prescribing scorecards.
MGB Biopharma Announces Successful Phase 2 C. difficile Candidate Trial
A dosage of 250 mg twice daily for 10 days was confirmed for the next phase of trials after achieving initial and sustained cure in 100% of patients.
Cefepime-Enmetazobactam Shows Promise for ESBL-Producing Enterobacteriaceae
The novel drug combines a fourth-generation cephalosporin with a novel extended-spectrum β-lactamase inhibitor.
Fosfomycin Does Not Demonstrate Non-Inferiority for E. Coli. Bacteremic UTI
Drug resistance has physicians racing to find alternative therapies for many infections. In a new non-inferiority study, fosfomycin was inferior to more common therapies.
Gram-Negative Infections Successfully Treated with Ceftazidime-Avibactam
Gram-negative bacteria can cause infections, are resistant to multiple drugs, and are increasingly resistant to most available antibiotics, the CDC says.
Oral Ibrexafungerp Effective & Well-Tolerated in FURI Phase 3 Trial
Oral ibrexafungerp could cut hospital stays for patients with invasive candidiasis infections.
Comparing Sensitivities: RT-PCR Versus Rapid Influenza Diagnostic Test
It is known that the type of respiratory specimen, sampling environmental factors, and time from symptom onset impact the sensitivity of rapid influenza diagnostic tests.
Study Finds Variability in Cefiderocol Pharmacokinetics
Investigators say they consider cefiderocol a candidate for therapeutic drug monitoring.
RESTORE-IMI 2: Imipenem/Cilastatin Relebactam Non-inferior to Piperacillin/Tazobactam for HABP/VABP
The data were released as part of the now-cancelled European Congress of Clinical Microbiology and Infectious Diseases.
Is Risk of Colorectal Cancer Linked to Certain Blood Infections?
Previous research has suggested an association between bacteria from the Bovis group streptococci, Clostridium septicum and colorectal cancer
Tracing Scarlet Fever Transmission in English Classrooms
Investigators have hypothesized that scarlet fever transmission is driven by pediatric cases with symptomatic disease.
Vaccinoscopie Europe Survey Evaluates Parental Views on Vaccination
A new survey found that parents in Spain were the most supportive of vaccinations when compared with their counterparts in 4 other European countries.
Study Finds Pets Not a Substantial Reservoir for Human Multidrug-Resistant Infections
Whole genome sequencing revealed little overlap between MDROs found in pets and pet owners.