Skin & Soft Tissue Diseases

Verrica received a Complete Response Letter from the FDA regarding their New Drug Application for the topical molluscum contagiosum treatment, VP-102.

Using real-time genetic surveillance, investigators found bacterial infections rapidly develop resistance to antibiotics, only to have these gene mutations disappear within a few days of switching to a different treatment.

Shortages of health care workers and an increase in COVID-19 cases has put a severe strain on the health care system. Thus, the opportunity to reduce the hospitalizations for other conditions and expand outpatient treatment opportunities should be welcomed.

A case series observation study found a slightly higher risk of Guillain-Barre syndrome among Medicare beneficiaries within 42 days after receiving the recombinant zoster vaccine Shingrix, but no changes are needed to guidance recommending the vaccine, investigators said.

This approval of the non-live, recombinant sub-unit adjuvanted vaccine, Shingrix, is for the prevention of shingles in adults aged 18 years and older with increased risk of immunodeficiency or immunosuppression.

This therapy becomes the first single-dose infusion to treat acute bacterial skin and skin structure infections (ABSSSI) in pediatric patients from birth.

CDC and WHO Data shows a 50% increase worldwide from 3 years ago.

“The compound appears to be safe and well-tolerated, [and we observed] excellent efficacy based on a very small sample size,” Peter G. Pappas, MD, said.

A closer look at the 2018 enterovirus A71 outbreak in Colorado highlights the need for non-sterile site testing to detect infections.

Treating parents colonized with S aureus reduced neonatal colonization with concordant S aureus strains when compared to placebo.

How many nursing homes have these microbes?

Global efforts to eliminate measles took a step backward, with the number of cases rising to 353,236 in 2018, up 167% from 132,413 cases in 2016.

Measles infection leaves patients vulnerable to a wide range of other pathogens by destroying antibodies for months or even years, according to a new study.

Treating patients who have skin and soft tissue infections with a single dose of oritavancin may lower hospital admission rates compared to vancomycin, at a similar cost.

New research found enterovirus antibodies in dozens of patients diagnosed with AFM and ruled out other viruses, offering more insight into the cause of the mysterious polio-like illness.

Although use of gowns and gloves in targeted settings may still be helpful in preventing health care-associated infections, contact precaution policies in VA long-term care facilities had no impact on MRSA acquisition.

The announcement came just 1 day after health officials in New York State declared the end of the Rockland County measles outbreak.

Two late breaker abstracts at IDWeek 2019 provide an in-depth analysis of the 2018-19 measles outbreaks in the state of New York.

According to the CDC, there were no new cases of measles reported during the week of September 6-12, 2019.

Investigators have presented the microbiological, efficacy, and safety results in the pooled intravenous drug use vs non-intravenous drug use patients in 2 phase 3 ABSSSI studies, OASIS-1 and 2.

A new study of college-aged individuals demonstrated insufficient immunity in a fraction of participants who were vaccinated against mumps in childhood.

The European Regional Verification Commission for Measles and Rubella Elimination concluded that Albania, Czechia, Greece, and the United Kingdom have lost ground in the fight to eradicate measles.

Evidence demonstrates that antimicrobial therapy with an anti-staphylococcal β-lactam antibiotic is the gold standard for treatment of SAB caused by MSSA, but confusion about which agent—particularly cefazolin versus an anti-staphylococcal penicillin—is preferred remains an unanswered question

As outbreaks of vaccine-preventable diseases grow, it is important to review vaccination recommendations by age group.