Antimicrobial Stewardship

Both noncarbapenem β-lactams and carbapenems produced good outcomes in UTI from β-lactamase-producing Enterobacterales.

Series-specific antibiotics can be far less effective if there are other microbes present.

Engaging in antimicrobial stewardship programs led to a reduction in antibiotic usage in long-term care facilities, potentially reducing the growing risk of antibiotic resistance.

The phase 3 results for its antibiotic, cefepime-taniborbactam, demonstrated it met its primary endpoint and the company says it is on track for a fourth quarter 2022 FDA NDA.

Using real-time genetic surveillance, investigators found bacterial infections rapidly develop resistance to antibiotics, only to have these gene mutations disappear within a few days of switching to a different treatment.

Few patients hospitalized for COVID-19 developed concurrent infectious diseases or required antibiotics.

For the first time, a research team mapped C difficile’s outer “S-layer,” finding the dangerous bacteria’s chainmail-like shell enables it to be highly resistant.

In the latest column from SIDP, handshake stewardship prioritizes face-to-face communication between frontline providers to enable feedback to assess the appropriateness of prescribed antimicrobials.

The 2019 Strategic Plan of the Infectious Diseases Society of America lays the groundwork for understanding prescribing practices.

Latest update of the bill introduced in the House November, but no word on a potential vote yet.

Shorter durations of antibiotic therapy demonstrate similar efficacy and may improve safety compared with longer courses for certain infections.

Investigators examined the efficacy and safety of carbapenems vs select novel antibiotics for treatment of cUTI.

To reduce antimicrobial resistant pathogens, nursing homes should carefully monitor their use of hospital-grade antibiotics.

Hospitals with lower c difficile antibiotic usage averaged shorter length-of-stay than hospitals that prescribed more antibiotics.

More than 1.2 million people were estimated to have died in 2019 as a direct result, and that antimicrobial-resistant infections played a role in millions more.

In the latest column from SIDP, the authors discuss having leaders to help navigate school and beyond.

Matt Henn, chief scientific officer at Seres Therapeutics, discusses new ways of targeting infectious diseases and antimicrobial resistant infections.

Risk of inaccuracy with pulse oximeters and clinician knowledge gaps in people of color may affect sepsis evaluations and impact treatment plans.

Antimicrobial resistance is “the silent pandemic,” Dr. Leonard Friedland says, and vaccines are how we fight it.

The website, LearnAntibiotics.com, is a supplemental tool offering guides, practice exams, and other resources to help students, residents, or practicing professionals with infectious diseases pharmacotherapy.

The federal agency will provide $22 million in funding to organizations worldwide dedicated to identifying next crisis.

Neonatal vancomycin trial found loading with more frequent dosing over shorter time comparable to standard regimen but adversely affected hearing.

The Infectious Diseases Society of America (IDSA) released new expert-informed guidelines for treating antimicrobial-resistant AmpC β-lactamase-producing Enterobacterales (AmpC-E), carbapenem-resistant Acinetobacter baumannii (CRAB), and Stenotrophomonas maltophilia infections.

The report on antimicrobial resistance finds new therapeutics are "essential to future of clinical medicine" but may not be viable in present market.

As providers were challenged to care for patients with severe COVID-19 In the first year of the pandemic, antibiotic usage increased. Listen to clinicians talk about this specific challenge and how prescribing practices evolved over time.

The report assesses progress of a US national action plan to combat antimicrobial resistance, called for by 2015 World Health Assembly.

From its origins as a serendipitous discovery to being successfully prescribed for nearly a century, antibiotics remain a foundation of medicine. However it has major ongoing challenges including the rise of superbugs and the development of antimicrobial resistance (AMR). There are some prospective strategies to combat AMR on the horizon.

Providers and key stakeholders weigh in on this significant topic.

The European Center for Diseases Prevention and Control published data today showing the greatest decrease in antibiotic consumption in 2 decades coincided with the COVID-19 pandemic.