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From Pandemic to EndemicA research agenda focusing on breakthrough infections, reinfections, severity, and sequelae is needed to inform clinical practice when COVID-19 emphasis shifts from eradication to living with the disease.
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FDA Approves Combination Antibiotic for Treatment of Complicated Urinary Tract InfectionsCefepime-enmetazobactam (Exblifep, Orchid Pharma) was given the federal nod for the indication of treating complicated urinary tract infections (cUTI) in adults.
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SIGA Technologies' Trial Results Benefits Mpox Treatment Despite Not Meeting Primary EndpointThe impact of including patients with advanced disease and the role of comprehensive care in the PALM 007 clinical trial, which evaluated the antiviral tecovirimat for treating monkeypox in the Democratic Republic of the Congo.
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Community-Acquired Candida Glabrata Empyema: An Atypical Diagnosis Not to MissAlthough this patient had none of these common risk factors associated with Candida empyema, she did have other factors predisposing her to fungal colonization and subsequent infection.
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IV Push Administration for Outpatient Parenteral Antimicrobial TherapyInvestigators designed a quasi-experimental pre- and post-intervention analysis comparing a pre-intervention cohort receiving IV drip antibiotic infusion with a post-intervention cohort receiving IVP administration.
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The Significance of WHO Declaring Mpox a Global EmergencyMitch Wolfe, MD, former Chief Medical Officer of CDC, offers some insights on mpox including the benefits of declaring a global emergency, disease transmission, and considerations for both the US public and clinicians.
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Barriers to Health Care Transition in Adolescents and Young Adults With Early Acquired HIV InfectionUnique challenges can affect the success of the shift from pediatric to adult care settings.
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Multidisciplinary Perspectives on HIV TreatmentA multidisciplinary panel concludes a discussion on best practices for managing patients with HIV in various healthcare settings and overcoming social health disparities.
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SURE1 and REASSURE Trials Paved Way for FDA Approval of OrlynvahCorey Fishman and Steven Aronin, MD, discussed trial highlights of Orlynvah for uncomplicated urinary tract infections and outlining plans to seek partners for a market launch to address antibiotic resistance and enhance patient treatment options.
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Top 5 Tips for Teaching ID LearnersThe latest article from SIDP offers a Top 5 list of how to precept a learner on an infectious disease rotation.
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Combination Antifungal for Invasive Mucormycosis: Yay or Nay?There is limited and conflicting data regarding the role of combination antifungal therapy for treatment of invasive mucormycosis.
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Maternal COVID-19 Vaccination, Infection Boosts Infant Antibody ResponseNatural infection plus COVID-19 vaccination in pregnant mothers conferred more durable antibody responses in infants than natural infection alone.
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What to Expect With Influenza in the Era of COVID-19Here are some insights into this upcoming 2021-2022 influenza season as well as concerns of the twindemic and addressing both the seasonal and pandemic viruses simultaneously.
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Oral Norovirus Gastroenteritis Vaccine VXA-GI.1-NN Shows EfficacySean N Tucker, PhD, highlighted that VXA-GI.1-NN demonstrated safety and efficacy in reducing norovirus infections, marking a potential treatment in prevention for a diverse range of demographics.
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HIV and Aging in the Era of Antiretroviral Therapy: Considerations in Clinical CareWith the population of adults with HIV growing older, incorporating age-based screenings, comprehensive assessments, and morbidity management into routine HIV care is essential in improving health outcomes and quality of life.
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Nonventilator Hospital-Acquired Pneumonia: Epidemiology, Prevention, and Where It Is NowThe management of hospital-acquired pneumonia requires use of preventive bundles, mitigative of risk factors, and prompt diagnosis with initiation of treatment when highly suspected.
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What We Know But Still Have to Learn About Long COVIDDespite advances in understanding and treating Long COVID, many questions about its mechanisms, susceptibility, and varied recovery patterns remain unresolved, underscoring the need for continued research.
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Clinical Considerations in Conducting Antifungal Susceptibility TestingAccess to antifungal susceptibility testing (AFST) remains limited in the United States. Therefore, providers must recognize clinical situations where AFST will provide its greatest value. In the latest article from SIDP, infectious disease pharmacists offers some insights on this subject.
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A Case of Mycobacterium Chimaera Infective EndocarditisNonspecific, nondolent symptoms make this disease difficult to diagnose.
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A Review of the Currently Available Monoclonal Antibodies for COVID-19Outside of vaccines, these underutilized therapies are the best defense against severe disease.
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Celebrating 30 Years: The Past, Present, and Future of the Society of Infectious Diseases Pharmacists (SIDP)Introducing “Bench to Bedside With SIDP,” a new column covering everything from antimicrobial stewardship and pharmacokinetics/pharmacodynamics to mentorship, preceptorship, and more.
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A Viral Colonial Legacy: HIV, Monkeypox Emerged Due to Ongoing Colonial Viral NeglectSimilar to HIV, the colonial and postcolonial history is fundamental to the biology of this monkeypox outbreak.
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Merck's Clesrovimab Shows Effectiveness in RSV Prevention for InfantsAnushua Sinha, MD, discussed the findings, highlighting a 60.4% reduction in medically attended lower respiratory infections and significant decreases in RSV-related hospitalizations.
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SPREADing the Love: The Importance of Mentorship in PharmacyIn the latest column from SIDP, the authors discuss having leaders to help navigate school and beyond.
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Restarting Therapy in Patients with HIVAddressing patients with HIV who have fallen out of care, Shauna Applin, ARNP, provides clinical insights on treatment options and best practices for restarting therapy.
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Tuberculosis Meningitis in an Immunocompetent PatientRead more about the case of a 71-year-old man who was admitted after presenting with cold-like symptoms for 3 weeks.
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Tips for Talking with Patients about Fecal Microbiota Transplant for Recurrent C. difficile InfectionsTo close the discussion, experts on C. difficile infections discuss how they talk with patients about fecal microbiota transplantation.
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A Case of Varicella-Zoster Meningitis Causing Postoperative Fevers After Umbilical Hernia RepairDue to worsening headaches and unrevealing cross-sectional imaging and ascites fluid analyses, this patient's differential evolved toward a central nervous system source.
