Michaela Fleming

The FDA has approved a supplemental new drug application for micafungin for the treatment of invasive candidiasis in pediatric patients under 4 months of age.

Treating parents colonized with S aureus reduced neonatal colonization with concordant S aureus strains when compared to placebo.

According to a new report issued by the WHO, the global incidence of cholera cases decreased by 60% in 2018.

The Bacille Calmette-Geurin vaccine is typically administered intradermally, which may not generate enough T cells to elicit strong immune responses in the lungs to effectively protect against TB.

The FDA has issused a complete response letter to ViiV Healthcare for cabotegravir/rilpivirine.

Piperacillin/tazobactam and meropenem are both accepted as options for empiric antibiotic therapy due to their broad-spectrum activity

A team of pharmacists at Baptist Hospital reported that improving penicillin allergy documentation and increasing the use of β-lactams had potential cost savings of $21,468 over a 3-month period.

A team of investigators set out to identify whether a risk prediction model that was developed at Novant Health could accurately identify individuals at a high-risk for health care-associated C diff infection.

imipenem/cilastatin plus relebactam was approved for the treatment of cUTIs and cIAIs in adult patients with limited or no available treatment options.

This approval allows ceftolozane/tazobactam to be used to treat hospital-acquired bacterial pneumonia (HABP) and ventilator-associated bacterial pneumonia (VABP).

In August, the FDA approved lefamulin (Xenleta) for the treatment of CABP after results from 2 phase 3 studies showed that the novel antibiotic was noninferior to existing treatment options.

In April, the US Food and Drug Administration (FDA) approved dolutegravir plus lamivudine as a complete 2-drug regimen for treatment naïve adults with HIV-1.

The difference in outcomes was 4.7% with a 95% confidence interval on that difference of -10.3% to 1.0%. This fell short of non-inferiority which required that the lower limit of the difference in the outcome rates be >-10%.

A new app is intended to crowdsource medical information regarding life-saving interventions with FDA-approved drugs as well as facilitate the development of novel drugs for neglected infectious diseases.

The test is a new diagnostic tool that uses bacterial viability and a novel technology to detect bacterial colonization of Methicillin-resistant Staphylococcus aureus.

On December 1, 2019, international health organizations reflect on the advancements of the HIV/AIDS research field and acknowledge the challenges that still remain.

The survey was designed to provide more information on beliefs and perceptions toward HIV among Generation Z and millennials in the United States.

In this novel type of outbreak, contamination was not isolated to a single food or facility, suggesting industry-wide contamination.

A new commentary describes the EEE virus along and points to research and development that is needed to address the growing threat of the virus and other vector-borne conditions.

Thus far there have been 11 outbreak-associated cases of hepatitis A in Indiana, Nebraska, and Wisconsin.

The sepsis alert system works by monitoring changes in patients’ temperatures, heart rates, and glucose levels, and notifying clinicians of abnormalities through electronic health records.

Existing evidence has suggested a strong biological link between HIV and herpes simplex virus 2 infection.

After analyzing electronic medical records from 161 patients across 90 VHA sites, investigators determined that patients initiated 94% of conversations about PrEP.

The vaccine candidate, TAK-003, is based on a live-attenuated dengue serotype 2 virus, which provides the genetic “backbone” for all 4 serotypes.

Prequalification status indicates that the vaccine meets the WHO’s standard for efficacy, safety, and quality.

Inmates at an NJ facility have their HIV treatment needs met while incarcerated but the lack of transitional care coordination has led many individuals to fall off of the care continuum upon release.

As HIV treatment shifts into primary care, it is important to educate NPs on HIV care and prevention in order to maintain recent gains towards ending the HIV epidemic.

“My story is important only because it proves that HIV can be cured. And if something has happened, once in medical science, it can happen again,” Brown told Contagion®.

People living with HIV are twice as likely as those who do not have HIV to develop cardiovascular disease, yet recent data suggest this population does not meet recommended levels of physical activity.

The Cooper Early Intervention Program Expanded Care Clinic observed that the gap in retention in care among patients with HIV was reduced from 15% to 10% over a span of 3 months.