How Can Photodynamic Therapy Challenge Microbial Resistance of Localized Infections?

Caetano P. Sabino, BSc, PhD Student, Clinical Analysis, School of Pharmaceutical Sciences, University of Sao Paulo, explains how photodynamic therapy can be used to challenge microbial resistance of localized infections.

Interview Transcript (slightly modified for readability)

“It’s really questionable whether any resistance can be developed against photodynamic therapy; as long as we are not selecting those drug-resistant bugs in the wounds anymore through chemotherapy, we are just killing them all in the same pattern. We are just living behind the drug-resistant selection and spread, and if we could also manage the dissemination of drug-resistant genes through plasmids, we can end up with dissemination of cross-interaction in between bacteria [and] the spread of drug-resistant genes. We are just blocking the thing in the beginning.”