Yale’s Section of Infectious Diseases within the Department of Internal Medicine engages in comprehensive and innovative patient care, research, and educational activities for a broad range of infectious diseases. The section’s 180+ faculty, trainees, and staff is dedicated to a patient-centered and equitable approach to healthcare, with high-level clinical and scholarly activity across the spectrum of infectious diseases.
Physicians’ Use of Fecal Microbiota Transplant for Recurrent C. difficile Infections
Members of the panel discuss when and where they tend to utilize fecal microbiota transplantation for recurrent C. difficile infections in clinical practice.
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Utilization of Fecal Microbiota Transplant Products in Clinical Practice
Experts on the treatment of patients with C. difficile infections provide insights on the implementation of fecal microbiota transplant products into clinical practices.
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Safety of Fecal Microbiota Options and Transfer of Food-Borne Allergens
The panel provides insights on common adverse effects associated with fecal microbiota transplantation and analyzes the possibility of FMT products carrying pathogens or food-borne allergens.
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Paul Feuerstadt, MD, FACG, AGAF, discusses the key findings from the phase 3 ECOSPOR clinical trial for fecal microbiota spores, live-brpk oral capsules (VAS).
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Data on Fecal Microbiota, Live-JSLM (RBL) for C. difficile Infections
Sahil Khanna, MBBS, MS, discusses the effectiveness of live-JSLM (RBL) in preventing the recurrence of C. difficile infections.
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Recent Fecal Microbiota Transplant Approvals for C. difficile Infections
Carl V. Crawford, MD, provides a comprehensive overview of the two FDA-approved FMT therapies for patients with recurrent C. difficile infections.
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Fecal Microbiota Transplantation for C. difficile Infections
The panel review data from foundational studies on fecal microbiota transplantation in patients with C. difficile infections.
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Contribution of Unnecessary and Prolonged Antibiotic Use to Recurrent C. difficile Infections
A panel of experts on C. difficile infections discusses risks associated with antibiotic use, including vancomycin-resistant enterococci infections.
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Managing C. difficile Infections in the Clinic
Focusing on the treatment of patients with C. difficile infections, Carl V. Crawford, MD, provides clinical insights on medication tapering practices and therapies being utilized by clinicians.
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Factors Contributing to C. difficile Infection Recurrence
Matthew D. Sims, MD, PhD, FACP, FIDSA, discuss how antibiotics do not completely eliminate C. difficile infections, the drivers of recurrence, and new treatments that are addressing eubiosis and C. difficile spores.
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Treatment Guidelines for C. difficile Infection
Experts on C. difficile infections give an overview of the ACG and IDSA/SHEA treatment guidelines for initial infection, first recurrence, and subsequent recurrences.
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Diagnostic Tests for C. difficile Infections
Paul Feuerstadt, MD, FACG, AGAF, provides clinical insights on diagnostic testing practices for C. difficile infections, highlighting the EIA, GDH, and PCR assays.
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Patients at Risk for Recurrent C. difficile Infections and the Role of Environmental Factors
Sahil Khanna, MBBS, MS, outlines patients at risk for recurrent C. difficile infections, and Teena Chopra, MD, MPH, FACP, FIDSA, FSHEA, focuses on environmental considerations that can help prevent transmission.
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Risk Factors for C. difficile Infections
Carl V. Crawford, MD, outlines the risk factors for C. difficile infections, focusing on factors that affect the body’s microbiome or immune system, including antibiotics, age, comorbid conditions, exposures, and prior C. difficile infections.
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Recurrence of C. Difficile Infections
Teena Chopra, MD, MPH, FACP, FIDSA, FSHEA, and Matthew D. Sims, MD, PhD, FACP, FIDSA, provide clinical insights on the rate of recurrence of C. difficile infections and the impact on patients.
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Epidemiology of C. difficile Infections in the US
A panel of experts provide an overview of the epidemiology of Clostridioides difficile infections, highlighting diagnostic practices and the role of antimicrobial stewardship.
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