Self-Testing for HIV Proves Preferable, Easy Among IV Drug Users
Self-testing for HIV is fast and easy, and test kits can be completed at a health department with the help of staff or at home and dropped off later.
ViiV Healthcare Submits FDA Application for Triumeq for Kids With HIV
If the company gets approval it would be the first dispersible single tablet regimen containing dolutegravir.
Where Else Should PrEP Assessment Go?
As more agents expand the capability and variety of PrEP options, investigators consider what questions remain about the drug class.
Adding Long-Acting Injectable Options for HIV Management
Following the approval of cabotegravir-rilpivirine earlier this year, experts are looking forward to an expansion of the drug class for HIV.
Dolutegravir/Lamivudine Provide HIV Suppression Through 3-Year TANGO Findings
The combination therapy's non-inferior efficacy to heavier TAF regimens may indicate a greater embrace of 2-drug regimens for people living with HIV.
How To Prioritize Pediatric COVID-19 Vaccination
Monica McArthur, MD, PhD, discusses why to-be-authorized COVID-19 vaccine doses for children may not be tiered for patient risk as they were for adults.
Casirivimab and Imdevimab Benefits Hospitalized Seronegative COVID-19 Patients
New late-breaking data illuminate the specific efficacy of the combination monoclonal antibodies.
CYPRESS Trial: RSV Vaccine for Older Adults Elicits Robust Immune Response
The findings have supported the launch of a phase 3 trial called EVERGREEN, which is now underway.
HIV Mental Health, Substance Risk During the Pandemic
A conversation in consideration of the high-risk psychosocial comorbidities the aging HIV population may face through COVID-19.
Understanding Long-Term Pediatric SARS-CoV-2 Antibodies
A new study from IDWeek showed most observed children previously infected with SARS-CoV-2 retained antibodies over 6 months.
Increased Hygiene, Motivated by COVID-19, Led to Fewer C Difficile Cases
The COVID-19 pandemic led people to take hygiene and sanitation more seriously, causing a decrease in C difficile infections.
Ferring's Investigational Therapy RBX2660 Demonstrates Another Potential Offering for C Diff Treatment
A clinician provides an overview of the data on the microbiota-based live biotherapeutic, RBX2660, which in phase 3 studies has shown safety and reduction in recurrent C difficile infection (rCDI).
Risk Factors Associated with Readmission after COVID-19 Hospitalization
After an initial hospitalization for COVID-19, some patients may have specific risk factors that increase their likelihood of readmittance.
Determining Weight Gain on ART Therapy
Investigators wanted to understand this phenomenon with a group of antiretroviral (ART) naïve people with HIV (PWH).
Antimicrobial Resistance and Changes to the Gut Microbiome after International Travel
Massachusetts General Hospital investigated how international travel contributes to the contraction and carriage of antimicrobial resistance (AMR).
People Living With HIV Experience a Diminished Immune Response to COVID-19 mRNA Vaccines
Major predictors of response were CD4+ count, suppressed viral load, and whether the participant received the Moderna or Pfizer mRNA vaccine.
Delta Variant Causes Unprecedented COVID-19 Disease in Children
The Arkansas Health Department’s research showed that, as with the rest of the population, Delta is severely infectious for children.
Assessing Breakthrough Infections Associated with the AZD1222 Vaccine
Investigators examined asymptomatic infection and the duration of viral shedding in symptomatic breakthrough infections in a phase 3 study with the AZD1222 COVID-19 vaccine.
Molnupiravir Could Become the First Authorized COVID-19 Pill
Unpublished, interim phase 3 data show an approximate 50% reduction in hospitalizations and deaths versus placebo. Merck is expediting FDA application for the antiviral drug.
Diagnostic Stewardship: Appropriate Testing Leads to Efficient Diagnosis, Timely Therapy
This type of stewardship is a means of reducing unnecessary testing, getting the appropriate diagnosis more efficiently, and getting patients the appropriate therapy in a timely manner.
PROVENT Trial: AZD7442 as Long-Acting Pre-Exposure Prophylaxis Protects Against Symptomatic COVID-19
In the primary efficacy analysis, the risk of developing symptomatic COVID 19 was reduced by 77% with AZD7442.
Early 3-Day Remdesivir Regimen Reduces COVID-19 Hospitalization, Death by 87%
The study author of the late-breaking IDWeek findings discusses what the new data mean for using the antiviral to reduce COVID-19 burden.
Discontinuing Precautions in Asymptomatic, PCR-Positive COVID-19 Patients
A survey found most healthcare professionals would clear an asymptomatic patient with a positive PCR test if the patient met other criteria.
How COVID-19 Impacted HIV Testing in the Emergency Department
In a study looking at one urban South Florida hospital, the pandemic negatively impacted testing.
Racial, Ethnic Disparities in COVID-19 Incidence in People Living With HIV
A study found disproportionately higher COVID-19 cases in Black and Hispanic people with HIV across the US.
Remdesivir Reduces Mortality in Some Hospitalized COVID-19 Patients
A study’s findings support the use of the therapy earlier in the course of COVID-19 in hospitalized patients.
Prevention Training and Decolonization Reduced COVID-19 in Nursing Homes
Orange County, CA nursing homes that partook in either universal decolonization or prevention training had significantly fewer staff and resident COVID-19 cases than nursing homes that did not.
A Glimpse of Co-Infections and Antimicrobial Use in Hospitalized COVID-19 patients
During the pandemic, hospitalists prescribing patterns changed, reflecting new data, clinical experience, and the introduction of new therapies.
COVID-19 Hospitalization and Mortality Significantly Higher for Rural Populations
Investigators saw vastly higher rates of hospitalization and mortality for rural populations over urban even after adjusting the results for various factors.
Updated CDI Treatment Guidelines Change Prescribing Therapy
The Infectious Diseases Society of America’s (IDSA) 2017 guideline saw an increase in using vancomycin as a first line therapy for Clostridioides difficile (CDI).