News

Sky-high costs with little wiggle room to negotiate mean fidaxomicin remains underprescribed for recurrent C diff, despite favorable outcomes.

If approved on its March PDUFA date, rezafungin could be the first new Candida treatment option in over a decade.

The new guidance looks at preexposure and postexposure prophylaxis as well as treatment for COVID-19.

A recreation of a failed staph vaccine trial unveiled that previous exposure to S aureus made the vaccine candidate ineffective.

A new study demonstrated continuous neutralization after 3 doses.

“Vaccination coverage among pregnant women remains a priority,” the study authors noted.

Rapidly distributing vaccines to at least 1/3 of at-risk populations, in addition to increasing tasting and contact tracing, may adequately stop the spread of mpox.

In this week’s meeting, FDA is expected to ask their advisory committee to consider changes to simplify the vaccination schedule and look at delivering it annually, much like an influenza vaccine.

What factors contribute to post-COVID-19 conditions (“long COVID”)? Can vaccination before or after a COVID-19 infection decrease the risk of long COVID?

An analysis of the actions taken to combat antimicrobial resistance in 114 countries finds national action plans easier to develop than to implement.

A Chinese epidemiologist made this claim this weekend as the country gathers for its Lunar New Year celebrations.

Reported reasons adults had not received a bivalent COVID-19 booster dose differed across age groups.

Click on the slideshow images to read the full stories featured in this weekly infectious disease recap.

A mathematical modeling study for HPTN 083 demonstrated both forms of PrEP vs not taking anything remained efficacious in preventing infection.

Although vaccine rates overall remain high, a new report shows a reduction 2 years in a row, leaving thousands of children not vaccinated against vaccine-preventable viruses.

Tenofovir alafenamide (TAF) and tenofovir disoproxil fumarate (TDF), antiretroviral drugs used to treat HIV and hepatitis B, may be simultaneously depleting the energy of immune cells.

A retrospective study showed that exercise was found to have a protective association to adverse COVID-19 outcomes.

What is the hepatitis C treatment uptake among people who inject drugs?

Interleukin-6 receptor antagonists and antiplatelets are highly likely to improve long-term survival of critically ill adults with COVID-19, a recent study suggests.

Based on the Data and Safety Monitoring Board DSMB’s recommendation, the study will be discontinued.

Sepsis is the number 1 cause of death in hospitals. The FDA approval of IntelliSep, the first sepsis diagnostic tool, could change this.

With limited health care infrastructure and large swaths of remote areas, developing countries face difficulties in medical management with these viruses and parasitic diseases.

Therapies to reach a functional cure for hepatitis B virus may differ among the phases of hepatitis B, including new antiviral agents and immunomodulatory strategies, the study authors predicted.

This act designed to allow pharmacists and technicians the ability to administer certain vaccines without a prescriber order will lapse next year. A new report looks at vaccination trends in the US and how pharmacists are playing a vital role in administering vaccines.

With these results, the company plans to submit their investigational vaccine, MRNA-1345, for regulatory approval in the first half of 2023.

Tibetan Buddhist monks, who meditate regularly, had vastly different gut microbiomes than the non-meditating control group.

In this guest editorial, the author talks about the challenges associated with dealing with both health issues.

High levels of mucosal IgA antibodies in the airways were found to protect against COVID-19 reinfection for at least 8 months.

Preclinical testing suggests that a newly developed SARS-CoV-2 vaccine could protect against current and future variants.

This live-attenuated investigational vaccine was developed by Codagenix, which uses its codon de-optimization platform for its candidates.