Effectiveness of Clostridioides Difficile (CDI) Infection Prevention Strategies in Acute Care
A study on the impact of guidelines on reducing hospital-onset CDI incidence.
Hepatitis C Virus: Task Shifting and Screening
Clinicians discuss screening and treatment approaches for the disease.
Top 5 Infectious Disease Stories Week of March 23
FDA authorizes Ito Invivyd’s pemivibart (Pemgarda), insights on Sofosbuvir levels in pregnant women, the effectiveness of fidaxomicin vs vancomycin for CDI treatment, and more this week from Contagion.
CDC Issues Health Advisory Over Increasing Invasive Meningococcal Disease Incidents
A surge in meningococcal disease cases linked to Serogroup Y.
Moderna Demonstrates Positive Results from Phase 3 Trial of its Next-Generation COVID-19 Vaccine
The company's latest investigational vaccine induced a greater immune response compared to its FDA approved Spikevax product.
Respiratory Syncytial Virus (RSV) Vaccination in Older Adults
Impact of the RSVPreF3 vaccine on respiratory illness in older adults in the US.
Completed Enrollment in Phase 3 SUNRISE-3 Trial for Bemnifosbuvir COVID-19 Treatment
Atea Pharmaceuticals bemnifosbuvir aims to help high-risk COVID-19 patients with a new oral option.
Assessing COVID-19 Rebound Post Antiviral Treatments
A study conducted in China aimed to assess factors such as viral load rebound (VLR), reduction in cycle threshold values, time until VLR, and symptom rebound.
Long-term Immunogenicity and Booster Response in Ebola Vaccine Regimen
Phase 2 study of healthcare workers' safety in high-risk populations.
Why Aligning Laboratory Professionals and Infectious Disease Clinicians Can Deliver Favorable Diagnostics, Treatments
In today’s world of sophisticated, complex tests, an evolving relationship between laboratory professionals and clinicians can aid in providing a quicker diagnosis and help to achieve better patient outcomes.
New Approach in Mycobacterial Infection Treatment
The potential of enzyme cocktails for enhanced mycobacterial infection management.
Expanding the Antibiotic Stewardship Team Can Lead to Greater Adoption of Practices
There is value in leveraging the contributions of nurses, laboratorians, and informaticists in antimicrobial stewardship.
The Role of Helicobacter Pylori Adhesin A (HpaA) in Gastrointestinal Diseases
Latest discoveries around HpaA's implications for immune response and disease progression.
FDA Approves First Molecular Test to Screen for Malaria in Blood Donors
The assay, the cobas Malaria test, is manufactured by Roche, and will be available in the United States at the end of Q2 2024.
Acute Hepatitis and Adenovirus in Children
Insights from a CDC study on challenges and research direction in pediatric hepatitis.
Rising Dengue Fever Cases Carry One Health Implications
The increase highlights the threat posed by climate change and the need for innovative preparedness, prevention, and mitigation tools.
Preventing the Entry of Hepatitis B and D Viruses
Bulevirtide's key role in blocking hepatitis virus entry.
Evaluating the Impact Tuberculosis Preventive Treatment in HIV Treatment Programs
The role of the US President’s Emergency Plan for AIDS Relief in combating tuberculosis (TB).
Navigating the Challenges of CMS AUR Reporting Mandates: Penalties, Progress, and Pitfalls
The long-term benefits of antimicrobial use and resistance (AUR) reporting is about improving patient care and combating resistance.
Preventing Mother-to-Child Transmission of Hepatitis C
Insights on Sofosbuvir levels in pregnant women.
Navigating a New Road Map for Infant RSV Prevention
A new strategy for universal infant immunization in the 2023-2024 RSV season faces implementation and medication access barriers.
And Then There Was One: HCV Elimination in the Coinfected Population
The evolution of treatment for hepatitis C virus during the past 15 years has been astounding, and we now are able to talk about how HCV could be eliminated.
FDA Grants EUA to Monoclonal Antibody for PrEP of COVID-19 in Immunocompromised
The authorization was given to Invivyd’s pemivibart (Pemgarda), and it is indicated for adults and adolescents with moderate-to-severe immune compromised conditions.
What Is a Better Treatment Approach for Immunocompromised Hosts With Clostridioides difficile Infection?
Here is a review of the effectiveness of fidaxomicin vs vancomycin for CDI treatment in populations with immunocompromised conditions.
Top 5 Infectious Disease Stories Week of March 16
This week learn more about CDC's strategies to reduce waterborne diseases; the US change to a trivalent influenza vaccine; new data for Merck's pneumococcal vaccine; and how PCR testing can influence a patient diagnosis and outcome.
The Role of Moderna's Modified mRNA-1273.214 Vaccine in Children Against COVID-19
The efficacy of SPIKEVAX from Delta to Omicron protection in pediatric patients.
Ceftriaxone as Definitive OPAT for MSSA Bloodstream Infections
A cautious approach for now is warranted as well as a need for a randomized clinical trial.
Rapid Identification and Management of Clostridioides difficile in the Emergency Department
The impact of polymerase chain reaction (PCR) testing on patient outcomes.
A Chance to Improve Hepatitis C Care for PWID
Here is a review of an opportunistic treatment approach to HCV infection in this patient population in a European study and some of the potential challenges in applying it in the United States.
Long-Term Efficacy of Typhoid Conjugate Vaccines (TCV)
Phase 3 trial evaluates the impact of TCVs in high-risk populations.
