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In the fourth and final episode, the clinicians speak of the need for greater uptake of the RSV vaccines, overcoming an "RSV identity crisis," and the potential ancillary benefit of reducing bacterial infections.

Our experts discuss the potential subgroups who might benefit from the vaccines and their safety profiles.

In part 2 of a 4-part series, clinicians discuss the efficacy, and the mechanism of action of the approved RSV vaccines, including the newly approved Moderna vaccine, mRNA 1345 (mRESVIA).

This is the first in a series of discussions between medical peers around RSV vaccines and specifically the newly approved Moderna RSV vaccine for seniors.

Brii Biosciences presented new data from Phase 2 trials for chronic hepatitis B at EASL Congress 2024, revealing insights into the efficacy of BRII-179 as botha combined therapy and an additional treatment.

Presented at DDW 2024 by Ken Blount, the effectiveness of live biotherapeutic products in treating recurrent C difficile infections (rCDI), offering insights into microbiota alteration and prospects for management.

Exact estimates of hospitalization and fatality rates for SARS-CoV-2 are rare among populations without previous exposure, particularly within demographic subgroups.

Seres is selling their microbiota product to Nestlé and expects to make a smooth transition as they already have an existing partnership.

Innovative approach across opioid treatment programs bridges geographical barriers, achieving cure rates, and unlocking health benefits for underserved populations.

The company announced data this morning for its investigational mRNA-1083 vaccine and plans to continue collecting data and working towards submitting a Biological License Application (BLA) for it.

Purportedly higher sepsis mortality in safety-net hospitals reflects less a difference in acute care than opportunities to discharge to hospice.

Historically, pneumococcal vaccination in adults has been reserved for those at heightened risk, with adults bearing the cost compared to free childhood vaccinations.

The federal agency’s decision expands the vaccine’s eligibility to people 50 years of age and older, making it the first one for this age group.

A newly published study suggests that a 15-day regimen, while safe, did not statistically separate from a placebo comparator group in main outcomes for PASC of SARS-CoV-2 infection.

FDA VRBPAC recommends protection against JN1 for the fall COVID-19 vaccines, a multidrug-resistant form of gonorrhea gives cause for concern, piperacillin-tazobactam shown to have higher mortality than cefepime for sepsis, and more this week from Contagion.

This man was the first person globally to have been diagnosed with influenza A(H5N2).

Although there is a rise in the FLiRT family of mutations, the committee decided to seek protection against the older strain.

Ongoing surveillance from the CDC and FDA will continue to evaluate the risk of Guillan-Barré syndrome to guide further ACIP recommendations.

Atea pharmaceuticals is presenting data at a European liver conference this week showing a high efficacy for its combination therapy at 12 weeks post-treatment.

A continued clarion call is being sounded about the drug-resistant pathogen.

The organization included numerous bacterium that are seen as critical threats to patients.

The clearance rate varied across states, but were not close to the 2025 or 2030 goals across all jurisdictions.

Piperacillin-tazobactam was associated with higher mortality than cefepime for empiric treatment of sepsis among patients without indication of anaerobic infection.

The 2024-2029 5-year UK national action plan for antimicrobial resistance is the second to emerge from the 20-year strategy announced in 2019.

The FDA alerts against certain apricot seed products containing amygdalin, a potentially harmful compound, and the CDC highlights Salmonella outbreaks, underlining the necessity for proper hygiene and poultry handling.

FDA approves Moderna's RSV vaccine for seniors, young women struggling with recurrent C difficile over the years, FDA grants Karius test to assist diagnosing infectious diseases, and more this week from Contagion.

The company’s mRNA 1345 vaccine was given the nod by the federal agency and is indicated for seniors for the prevention of RSV-associated lower respiratory tract disease (RSV-LRTD).

CDC has been tracking New York City varicella outbreak among migrants with over 870 cases reported since October 2022.

This is the second case in Michigan and it is confirmed in another farmworker who worked with infected cattle.

The link between vancomycin susceptibility and decreasing sustained clinical response in C difficile infections.