News

A team at UCSF has created a model which estimates how many pediatric cases are going unnoticed in any US county at any time.

A trio of studies appearing in JAMA today now support steroid use to reduce mortality in patients with severe SARS-CoV-2 infections.

The test designed to detect SARS-CoV-2 will be available in Europe later this month and provides results in 15 minutes.

A pharmacokinetic and safety substudy found that the 50 mg film-coated adult dose of dolutegravir given once daily is safe and effective for children with HIV weighing 20 kg or more.

Adults appear to have a higher risk of IBD if they have been prescribed antibiotics, according to a new large study.

Heat Biologics CEO Jeff Wolf talks with Contagion about the firm's effort to develop a vaccine for the coronavirus which can potentially be administered for some seniors by taking advantage of prior immune mechanisms.

One effort to develop a SARS-CoV-2 vaccine focuses on combining antibody and T cell immunity, using a gp96 protein based technology.

The Roche test supports rapid molecular detection of acute HIV infection, with differentiation between HIV-1 and -2.

The company is recruiting up to 30000 Americans for AZD1222, its vaccine candidate, as it enters a late-stage trial.

A new analysis of excess deaths suggests the peak of the current pandemic in New York City had a death rate in the same league as the infamous 1918 influenza pandemic.

Analysis finds 2-day “lag” in case counts, potentially suggesting testing delays.

A new CDC Morbidity and Mortality Weekly Report adds information on seroprevalence of SARS-CoV-2 among health care workers in a 13-hospital multistate medical network between April and June of 2020.

A study team examined asthma prevalence in patients hospitalized for COVID-19 with population asthma prevalence and a 4-year average of asthma prevalence in influenza hospitalizations across the United States.

John F. Kokai-Kun, PhD, Director of External Scientific Collaboration at USP, discusses the recent report of SARS-CoV-2 reinfection.

Are COVID-19 patients getting early empiric antibiotics?

Mathematical modeling for tracing COVID-19 contacts can account for likely scenarios of inconsistent physical distancing and quarantine adherence

An estimate that 100K may have been infected by mid-March dwarfs official figures.

John F. Kokai-Kun, PhD, Director of External Scientific Collaboration at US Pharmacopeia, explains the fundamentals of convalescent plasma treatment for COVID-19.

Bhopal’s recent article, COVID-19 Zugzwang, was published in Public Health in Practice.

A refresher on the week's developments in the infectious disease drug & medical device FDA approval pipeline.

The FDA regularly posts updates on recalls, outbreak investigations, and related regulatory activities. Weekly, we identify which of those announcements might be most clinically relevant.

FDA expands usage to all hospitalized COVID-19 patients.

The 15-minute test was granted emergency authorization by the FDA earlier this week.

John F. Kokai-Kun, PhD, explains the supply chain and logistical issues limiting the scale of monoclonal antibody treatment.

John F. Kokai-Kun, PhD, Director of External Scientific Collaboration at US Pharmacopeia, explains the fundamentals of monoclonal antibody treatment.

A new report suggests a personalized approach to sepsis treatment, recommending prompt antimicrobial therapy for the sickest patients and a more personalize approach for those with less severe cases.

The short-lived designation of remdesivir as an Orphan Drug to treat COVID-19 exposed loophole in the Orphan Drug Act.

How can critically ill COVID-19 patients experience immune system “paralysis” when inflammatory processes are in overdrive?

Hospital admissions for stroke fell by nearly a third during March and April 2020 alone when compared with those months in 2019.

A study team assessed 4 methods of N95 mask decontamination, with results suggesting that proper procedure can allow the reuse of masks 2-3 times.