Pfizer and BioNTech Report 97% COVID-19 Vaccine Efficacy in Israel Population
The data additionally show a 94% prevention against asymptomatic SARS-CoV-2 infection, at a time when the country's dominant strain was the B.1.1.7 variant.
European Union Authorizes Janssen COVID-19 Vaccine
France announces a relaxation on restrictions involving international travel outside the EU.
WHO Issues EUL for Janssen COVID-19 Vaccine
This Emergency Use Listing (EUL) of this single-shot vaccine opens up the door to much of the developing world to gain access to it.
US Has Millions of AstraZeneca COVID-19 Vaccines Available
Though the product is authorized more than 70 countries, there is currently no reported US trial data, nor application for authorization to the FDA.
Do COVID-19 Survivors Need Only 1 of a 2-Dose Vaccination?
Strong immunologic responses to vaccination for SARS-CoV-2 in COVID-19 survivors suggest that first of 2-dose vaccination could suffice.
C diff Risk Increases with PPI Usage
According to one new study, proton-pump inhibitors (PPI) exposure demonstrated a moderate increase in the risk of community-acquired C diff infection.
Macrolide-Resistant Strains Identified in 40% of S. Pneumoniae Infections
Macrolide-resistant strains of Streptococcus pneumoniae account for almost 40% of infections overall, a new study found.
Home COVID-19 Testing Could Prevent Infections and Reduce Deaths
The analysis highlights the importance of high-frequency testing as a complement to social distancing, vaccination, and other mitigation strategies.
Improving Mental Health in Older Adults Living With HIV
Managing mental health in adults living with HIV is paramount during the COVID-19 pandemic.
Hepatitis B Vaccine Adherence Stronger in 2 Doses Compared to 3
Series completion rates were different among patient groups, the study authors observed.
Should TB Treatment Move into Long-Acting Injectables?
While at the earliest stages of potential development, long-acting/extended release (LA/ER) formulations for treatment and prevention of TB could be something to be studied in the future.
Biden Announces Purchase of 100 Million Janssen COVID-19 Vaccine Doses
The acquisition of the Johnson & Johnson pharmaceutical company's vaccine would likely be completed in the latter half of this year.
Impact of COVID-19 on HIV Testing in Children and Adolescents
Index testing declined in countries including Malawi, Lesotho and Zimbabwe.
Impact of HIV on Brain Structure and Function
Deep learning models identified the largest differences in resting state network topology occurred.
Neutralizing Antibodies in SARS-CoV-2 Infected Children
Plasma proteome confirmed the association between cellular and humoral SARS-CoV-2 immunity.
Proteomics May Identify Proteins Predictive of HIV Mortality
The prognostic proteins identified can serve as the basis of future pathway and network analyses.
Findings for Extended Dapivrine Delivery Phase 1 Trial Reported
Dapivrine (DPV) was studied in 1-month and 3-month durations.
Men Report Worse Respiratory, Inflammatory Status with SARS-CoV-2 than Women
Johns Hopkins data suggest men are being hospitalized more frequently with infection, and are facing more severe outcomes.
Single Dose of mRNA Vaccine May be Enough for COVID-19 Experienced People
MN titers showed a striking increase after just 1 dose in experienced subjects.
Using the MINMON Approach as a Safe and Simple Treatment for HCV
COVID-19 has further highlighted the need for innovative models that minimize face-to-face contact in HCV treatment.
HIV Maturation Inhibitor Findings Presented
ViiV Healthcare’s investigational therapy, GSK’254, demonstrated antiviral activity, safety, and tolerability in its phase 2a proof-of-concept findings.
Treating COVID-19 with Potent Neutralizing Antibodies
Convalescent plasma treatment was found not to improve survival or disease course in the patient group.
Why COVID-19 Booster Vaccines May Be Warranted This Year
A UK health authority representative discussed the possibility of a fall season booster to prevent another winter surge of cases.
Gut Barrier Integrity and COVID-19 Severity
Gut microbiome is known to release enzymes that degrade plasma glycans which regulate inflammation.
Viral Suppression in the Southern US
With the highest HIV incidence rate in this part of the country, the need to get people from diagnosis to timely antiretroviral therapy (ART) remains an urgent need.
HIV CRISPR Screen Provides Novel Dependency Factors
New research from the Emerman Lab at Fred Hutchinson shows potential for advancing HIV-1 life cycle understanding.
Inflammation Could Help Predict HIV Women Cardiovascular Risks
Presented at CROI, investigators have identified sex-modified inflammatory predictors of cardiovascular and VTE risks among patients with HIV.
Looking at an Investigational PrEP Treatment With an Implant Option
Merck has developed its investigational islatravir subdermal implant for prevention of HIV infection, and it is going to be studied for a long-term delivery of up to 1 year.
Treating ART-Associated Bone Loss With Alendronate
14 weeks of oral alendronate taken prior to ART had a sustained impact on prevention of bone loss at the hip.
Role of Immunosuppression in the Risk of Severe COVID-19
Increased hospitalization risk was driven mainly by the high burden of comorbidities in both groups.