CDC’s New Mask Guidance: Real-Life Considerations
The guidelines were welcomed by some, but infectious disease providers say caution is needed moving forward.
COVID-19 Surge in Japan Drives Mass Vaccination Efforts
India pushes 300,000 COVID-19 death mark as worries of black fungus loom.
Challenges in HIV Management and Therapy
A discussion on issues surrounding the treatment of HIV with Melissa Badowski, PharmD, MPH.
Investigational Clostridioides Difficile Therapy Demonstrates Superiority Over Placebo
Ferring Pharmaceuticals and Rebiotix reported results from a trial on their therapy, RBX2660, which shows promise as a Clostridioides difficile infection (CDI) treatment.
Moderna COVID-19 Vaccine Efficacious in Pediatric Population
The company plans to file for Food and Drug Administration (FDA) authorization for the 12-17 year old population in early June.
Public Health Watch: New HBV Vaccine Shows Promise in Phase 3 Trial
New shot fills a vital need, given poor efficacy of earlier options, researchers say.
Dengue Vaccine Candidate Provides 62% Efficacy for Children & Adolescents at 3 Years
TAK-003, from Takeda, is showing slightly improved protection among seropositive participants through its 36-month follow-up.
How Pharmacist-led Interventions Can Improve Discharge Antibiotic Use
A conversation on antimicrobial stewardship with Kushal Naik, PharmD, MBA.
COVID-19 Vaccines Reduce Asymptomatic Cases
Routine screening of employees at St. Jude Children’s Research Hospital show lower rates of asymptomatic SARS-CoV-2 infection among vaccinated workers.
Learning More About Long COVID
There is still much to understand in the cases for those who did not require hospitalization but have lingering symptoms that can cause quality-of-life issues.
Monoclonal Antibody Being Developed for Treatment and Prevention of COVID-19, Variants
An investigational therapy demonstrated neutralizing antibodies as well as protection against the virus in preclinical trials.
The Burden of Clostridioides Difficile
A study looked at hospital admissions of Medicare patients and saw a large percentage of recurrent Clostridioides difficile infections (rCDI) as the primary diagnosis.
Mandatory Stop Dates, Indication Documentation Do Not Impact Length of Antibiotic Therapy
No difference was observed in any of the outcomes and there was no impact on the duration of therapy.
Evaluating Safety and Efficacy Protocols of Graded Dose Challenge and Desensitization
GDC and DSENS were both seen to be safe and effective tools to optimize therapy in the study participants.
Shorter Prescription Stop Dates Do Not Influence Antibiotic Treatment Duration
An effort to increase stewardship showed that 5-day and 10-day prescription stop dates for antibiotics did little to influence actual therapy length and outcomes.
Developing a Severity Score to Better Assess COVID-19
A diagnostic analyzer was studied looking at 3 biomarkers to predict the level of COVID-19, and could potentially serve as a risk stratification tool.
Antibiotic Prescribing, Guideline Adherence May Vary by Care Setting
An assessment from the Cleveland Clinic shows prescribing concordant to guidelines can exceed 60% in certain facilities.
Antimicrobial Stewardship Opportunities in Non-Neutropenic Oncology Patients
Almost half of the participants in the study had an opportunity to improve their antibiotic regimen.
Effectiveness of a Pediatric Antimicrobial Stewardship Program in a Community Hospital
The pilot program was demonstrated to significantly reduce days of antibiotic therapy.
Pharmacist-led Intervention to Improve Antibiotic Use at Hospital Discharge
More than half of the pharmacist led interventions were accepted by providers during the intervention period.
Impact of COVID-19 on Outpatient Daily Life
A majority of the study participants experienced symptoms that interfered with activities of their daily life.
Understanding Recurrent Clostridioides Difficile Infection and Hospitalization
A large retrospective analysis of Medicare patients offers a glimpse of the incidence rates of this patient population and the burdens associated with it.
Tocilizumab Could Treat Cytokine Release Syndrome in Severe COVID-19 Patients
The IL-6 targeting monoclonal antibody is linked to improved inflammatory and hemodynamic markers in hospitalized patients.
Assessing Antimicrobial Stewardship Interventions on Discharge Antibiotic Regimens
Interventions implemented by pharmacists were more likely to be accepted by prescribers.
Fidaxomicin, Vancomycin Provide Similar C Difficile Initial Cure, Mortality Rates
A meta-analysis suggest the 2 first-line C diff therapies provide similar outcomes, yet differ in recurrent infection risk.
Utilizing an EMR to Increase Infectious Disease Consultations
Study finds communicating on Electronic Medical Record (EMR) led to follow-up with infectious disease providers.
Identifying Associated Risk Factors for Persistent Vancomycin Resistant Enterococcal Bacteremia
In-hospital mortality and recurrent bacteremia occurred in 58% and 17% of patients with persistent VRE BSIs.
Pharmacist-Led Flu Shot Screening Leads to Improved Community Immunization
A concerted effort to increase flu vaccination during the COVID-19 pandemic resulted in more protection among a high-risk population, as well as educational opportunities for pharmacy students.
Evaluating the Efficacy of Daptomycin and Ceftaroline for the Treatment of MRSAB
Rates of in-hospital mortality and days with bacteremia were similar between the two study cohorts.
FDA Authorizes Longer Refrigeration Period for a mRNA COVID-19 Vaccine
The federal agency elongates the time from 5 days up to 1 month for thawed out doses of the Pfizer-BioNTech vaccine.