The Burden of Clostridioides Difficile
A study looked at hospital admissions of Medicare patients and saw a large percentage of recurrent Clostridioides difficile infections (rCDI) as the primary diagnosis.
Mandatory Stop Dates, Indication Documentation Do Not Impact Length of Antibiotic Therapy
No difference was observed in any of the outcomes and there was no impact on the duration of therapy.
Evaluating Safety and Efficacy Protocols of Graded Dose Challenge and Desensitization
GDC and DSENS were both seen to be safe and effective tools to optimize therapy in the study participants.
Shorter Prescription Stop Dates Do Not Influence Antibiotic Treatment Duration
An effort to increase stewardship showed that 5-day and 10-day prescription stop dates for antibiotics did little to influence actual therapy length and outcomes.
Developing a Severity Score to Better Assess COVID-19
A diagnostic analyzer was studied looking at 3 biomarkers to predict the level of COVID-19, and could potentially serve as a risk stratification tool.
Antibiotic Prescribing, Guideline Adherence May Vary by Care Setting
An assessment from the Cleveland Clinic shows prescribing concordant to guidelines can exceed 60% in certain facilities.
Antimicrobial Stewardship Opportunities in Non-Neutropenic Oncology Patients
Almost half of the participants in the study had an opportunity to improve their antibiotic regimen.
Effectiveness of a Pediatric Antimicrobial Stewardship Program in a Community Hospital
The pilot program was demonstrated to significantly reduce days of antibiotic therapy.
Pharmacist-led Intervention to Improve Antibiotic Use at Hospital Discharge
More than half of the pharmacist led interventions were accepted by providers during the intervention period.
Impact of COVID-19 on Outpatient Daily Life
A majority of the study participants experienced symptoms that interfered with activities of their daily life.
Understanding Recurrent Clostridioides Difficile Infection and Hospitalization
A large retrospective analysis of Medicare patients offers a glimpse of the incidence rates of this patient population and the burdens associated with it.
Tocilizumab Could Treat Cytokine Release Syndrome in Severe COVID-19 Patients
The IL-6 targeting monoclonal antibody is linked to improved inflammatory and hemodynamic markers in hospitalized patients.
Assessing Antimicrobial Stewardship Interventions on Discharge Antibiotic Regimens
Interventions implemented by pharmacists were more likely to be accepted by prescribers.
Fidaxomicin, Vancomycin Provide Similar C Difficile Initial Cure, Mortality Rates
A meta-analysis suggest the 2 first-line C diff therapies provide similar outcomes, yet differ in recurrent infection risk.
Utilizing an EMR to Increase Infectious Disease Consultations
Study finds communicating on Electronic Medical Record (EMR) led to follow-up with infectious disease providers.
Identifying Associated Risk Factors for Persistent Vancomycin Resistant Enterococcal Bacteremia
In-hospital mortality and recurrent bacteremia occurred in 58% and 17% of patients with persistent VRE BSIs.
Pharmacist-Led Flu Shot Screening Leads to Improved Community Immunization
A concerted effort to increase flu vaccination during the COVID-19 pandemic resulted in more protection among a high-risk population, as well as educational opportunities for pharmacy students.
Evaluating the Efficacy of Daptomycin and Ceftaroline for the Treatment of MRSAB
Rates of in-hospital mortality and days with bacteremia were similar between the two study cohorts.
FDA Authorizes Longer Refrigeration Period for a mRNA COVID-19 Vaccine
The federal agency elongates the time from 5 days up to 1 month for thawed out doses of the Pfizer-BioNTech vaccine.
Moving Forward, Combo Tests Will Be the Answer
Kits created by companies like Cepheid and bioMérieux will aid in the testing and treatment of viral infections in the future.
Children With MIS-C Show Unique Immune System Signatures
Children who experienced MIS-C showed an elevation of certain adaptive immune responses that confer immunological memory.
Convalescent Plasma May Improve Survival in Severe COVID-19 Cases
Patients who received the therapy had half the rate of mortality at 28 days after treatment.
The EU Agrees to Open Up for Travelers
The European Union (EU) agrees to look at easing restrictions for travelers from outside the continent, depending on vaccine or country status.
Public Health Watch: Heparin, Analogs Outperform Remdesivir as COVID-19 Treatment
Studies are in early stages, according to the scientists at Rensselaer Polytechnic Institute (RPI) leading them.
Filter Made of Nanofiber Captures Nearly All Coronavirus Aerosols
The nanofiber filter was able to remove 99.9% of the coronavirus aerosols, while cotton masks only removed 45%-73%.
New COVID-19 Test Can Give Results Faster Than Currently Available Methods
The novel sensor system is able to detect the presence of a virus in just 1 second.
Monoclonal Antibodies Reduce Risk of Hospitalization From COVID-19
Patients who were most likely to suffer complications and received the therapy had a 60% reduced chance of hospitalization and death.
FDA Grants EUA for COVID-19 Testing for Asymptomatic People
A Roche test can be used in individuals not showing signs of symptomatic disease.
How Well Can Rotavirus Vaccines Protect Against RVGE?
A study shows countries with the highest income levels had greater vaccine protection against rotavirus gastroenteritis (RVGE).
The mRNA COVID-19 Vaccines Shown to be 94% Efficacious in Health Care Personnel
A new CDC study demonstrates effectiveness in a population with high exposure to the virus.