Hydroxychloroquine Fails to Show Efficacy for COVID-19 Prophylaxis
The trial consisted of non-hospitalized adults who indicated a high-risk or moderate-risk exposure to COVID-19 through the household or an occupational setting.
Chikungunya Vaccine Candidate Well Tolerated & Immunogenic in Phase 1 Trial
The vaccine had no serious adverse events reported in the 120 person trial.
Putting Remdesivir, Coronavirus Into Perspective
Why people may need to readjust their expectations around COVID-19 clinical data and drugs.
Zinc Not Impactful on HIV/AIDs Mortality Among Heavy Alcohol Users
Zinc supplements are widely available and have been linked with lower inflammation, but a new study finds it does not significantly lower mortality risk.
John Strotbeck: How Boathouse Sports Started Making PPE
John Strotbeck, Olympian and CEO of Boathouse Sports, explains how and why the outerwear company pivoted to PPE production at the start of the COVID-19 pandemic.
Contagion Live News Network: The Emerging DRC Ebola Outbreak
A review of the latest infectious disease news.
How to Prepare for Public Dissent from a COVID-19 Vaccine
An eventual COVID-19 vaccination should be prepared to face obstacles before distribution, so the groundwork for factual information dissemination should begin now.
Reviewing the Pharmacology and Biochemistry of Remdesivir for COVID
Sarah Jorgensen, PharmD, MPH, BCPS, BCIDP, AAHIVP, provides a deep dive on the pharmacology and biochemistry of remdesivir.
How Deadly Was the 2019-2020 Flu Season?
While COVID-19 may have impacted flu-like illness reporting, the CDC estimates there were between 24,000-62,000 related deaths this year.
Literature Review Examines SARS-CoV-2 Prevention Methods
A study team investigated the ideal physical distance for avoiding SARS-CoV-2 transmission and assessed the use of eye protection and face coverings in preventing acquisition.
New DRC Ebola Outbreak Emerging in Equateur Province
As of June 1, there have been at least 6 cases of Ebola detected in Mbandaka, a port city with a population of more than 1.2 million people.
FDA Grants Cefiderocol Priority Review for New Indication
Cefiderocol functions as a siderophore and has a novel mechanism of action which penetrates the outer cell membrane of Gram-negative pathogens.
Verifying Infectious Disease Data
Denise Bascow, MD, describes a platform for keeping up to date with the latest clinical information.
Optimizing Remdesivir Use for COVID-19
A look at the means by which clinicians are quantifying and evaluating the effects of the antiviral drug.
Coronavirus Could Have Reached US in January
New findings from the CDC show community transmission may have begun in the Pacific Northwest a full month before the first confirmed case.
Recapping the Remdesivir Rollout
It's been one month since the antiviral therapy was granted emergency use authorization. How has it affected COVID-19 care?
HIV Cure Research Has Slowed, But Still Progresses
The COVID-19 pandemic has put the brakes on HIV cure research, but investigators report recent progress and promising pathways nonetheless.
FDA Recalls: HeartWare HVAD Pump Outflow Graft
A compilation of key FDA recalls from the past week.
Contagion Live News Network: More Hydroxychloroquine Concerns
A daily infectious disease news update
Systematic Review Highlights Hydroxychloroquine Ambiguities
Investigators sought to summarize evidence about the benefits and harms of hydroxychloroquine and chloroquine as treatments or prophylaxis of COVID-19.
Kelly Cawcutt, MD: COVID Has "Revolutionized" Health Care
Kelly Cawcutt, MD, MS, shares her thoughts on COVID's impact on health care, as well as why it's so important for clinicians to take breaks.
FDA Approves Pediatric Formulation of Bedaquiline for Multidrug-Resistant TB
The FDA has approved bedaquiline for use in combination therapy for the treatment of patients 5 years and older with pulmonary multi-drug resistant tuberculosis.
CIDRAP Advocates for COVID-19 "Smart Testing" - Public Health Watch
A new report outlines the proven steps needed to implement a national strategy for SARS-CoV-2 screening.
ACE Inhibitors, ARBs Do Not Worsen COVID-19 Risk
Early links between heart disease and diabetes and coronavirus severity caused some to fear that the 2 classes of medication might worsen outcomes during the pandemic. A systematic review finds little evidence to back those fears.
Contagion Live News Network: Does ACE2 Explain COVID-19 Pediatric Incidence?
A brief on our top stories from May 28, 2020.
FDA Grants Emergency Use to Quest Diagnostics COVID-19 Self-Collection Kit
Collected specimens can be tested with the Quest Diagnostics SARS-CoV-2 RT-PCR test to have received EUA from the FDA earlier in March.
Continuing Antibiotic Stewardship in a Pandemic
Debbie Goff, PharmD, describes how antimicrobial stewardship work has continued during the COVID-19 pandemic.
Why Comparing Flu and COVID-19 Severity Is Not Equivalent
Experts argue that though public officials may liken coronavirus to "just another flu," the true numbers show a stark difference.
Tuberculosis Antibacterial Courses Ineffective in Minimizing Antibiotic Use
Investigators reviewed 8 studies which had various treatment duration, number of antibacterial courses, and definitions of response to treatment.
Less Nasal ACE2 May Explain Fewer COVID-19 Cases in Children
Less ACE2 in nasal epithelium in children could present barrier to SARS-CoV-2 and explain the lower observed rate of pediatric infections.