PrEP Can Be Cost-Effective in Sub-Saharan Africa
Risk-informed PrEP would reduce HIV incidence by 49 percent over the next 50 years, the study authors found.
Lenacapavir for HIV Infection in a Multidrug-Resistant Study Cohort
Could lenacapavir be the answer for people with multidrug-resistant HIV infection? Principal investigator Sorana Segal-Maurer discusses the promising trial results in this challenging cohort (Interview part 1).
Assisting With International Health Care Needs
Although the pandemic halted many medical mission assignments, these opportunities and others are becoming available to help those geographic areas with acute needs.
Neutralizing Antibodies in Children a Year After COVID-19 Infection
At 1 year after COVID-19 infection, children’s neutralizing antibodies only differed by vaccination status.
In C Diff, New Attention Being Paid to the Role of the Virome
Most of the discussion around fecal microbiota transplantation has focused on bacterial communities, but new advances have shed more light on the role of the virome.
FDA Approves Baricitinib for Certain Hospitalized Adults With COVID-19
The federal agency authorized the therapy as a standalone treatment via a revised EUA in July of last year.
Novavax Reports 2022 First Quarter Earnings, COVID-19 Vaccine Rollout
Despite a significantly slower than expected COVID-19 vaccine rollout, Novavax reports early 2022 as its first profitable quarter.
Gestational Age at COVID-19 Vaccination Affects Baby’s Antibodies
The higher the gestational age when pregnant women received a COVID-19 vaccine, the higher the serological titers at birth.
Maternal Immunization with Investigational RSV Vaccine Conferred Protection to Infants
Active immunization of pregnant women with investigational vaccine protected infants from RSV from birth through at least 6 months.
A Warning of Climate Change’s Potential Effect on Public Health, But Will We Listen?
Research suggests a political disconnect on the status of global environment that could impact health response during a crisis.
COVID-19 Vaccine Immune Response in Children with HIV
Children living with HIV had a similar immune response to mRNA COVID-19 vaccination as children without HIV.
Do COVID-19 Rapid Tests Detect Variants of Concern?
Investigators examined whether rapid antigen tests were less sensitive to variants of concern. Though the tests detected Omicron, all but 1 were less effective in detecting the Delta variant.
Monoclonal Antibodies for Post-Exposure Prophylaxis Could Saves Lives and Money
Using monoclonal antibodies as post-exposure prophylaxis could be a cost-effective approach to battling COVID-19 in scenarios that include high transmission of susceptible variants, a new study suggests.
NIH Launches Vaccine Trial for Epstein-Barr Virus
A member of the herpes family, Epstein-Barr virus is the primary cause of infectious mononucleosis and may also cause certain cancers and autoimmune diseases.
Public Health Watch: Many COVID-19 Patients Incorrectly Prescribed Corticosteroids
JAMA study reveals use of dexamethasone and others in non-hospitalized patients with mild to moderate illness.
Why Are Some Lungs Protected Against COVID-19?
Investigators identify 11 crucial “protection-defining genes” that prevent a severe disease response to COVID-19 infection.
MAD-ID: Dedicated to Antimicrobial Stewardship
The organization has its upcoming antimicrobial stewardship meeting in less than two weeks, and offers professional education and training in infectious diseases with a special emphasis on antimicrobial stewardship.
FDA Limits Use of J&J COVID-19 Vaccine
The federal agency revised the vaccine’s Emergency Use Authorization after an analysis of the risk for thrombosis with thrombocytopenia syndrome (TTS).
Public Health Watch: Second Thoughts on a Second Booster?
The number of Americans who opt for an additional booster dose of a COVID-19 vaccine may be limited.
Mix and Matching COVID-19 Vaccine Boosters
Researchers looked at the serial use of homologous and heterologous boosters in open-label clinical trials across 10 US sites.
Public Health Watch: FDA Uses ‘Extrapolation’ in 1 in 4 Drug Approvals
Though a valid scientific approach, it may assume benefits incorrectly, researchers warn.
Novel Strategies to Identify and Eliminate Latent HIV Cells
HIV reservoirs can remain dormant, reigniting infection at an opportune moment. New strategies seek to reignite these viral reservoirs so they can be identified and destroyed by the immune system.
C Difficile May Spread Zoonotically Between Pigs and Humans
Antibiotic-resistant strains of the dangerous superbug C difficile have been identified in pigs and humans, suggesting zoonotic transmission is possible.
FDA Approves 2 Vonoprazan Treatments for Helicobacter Pylori Infection
Today, the FDA approved vonoprazan dual and triple therapies, developed by Phathom Pharmaceuticals to treat adults with H. pylori infection.
Better Sampling to Reduce C Difficile Misdiagnosis
Improving stool sample collecting and testing reduced C difficile underdiagnosis.
Outpatient COVID-19 Visits and Antibiotics: Did We Overprescribe?
Researchers sought to assess antibiotic prescriptions associated with COVID-19 outpatient visits in Medicare beneficiary patients over the course of a year during the pandemic.
COVID-19 Pandemic Disrupted Dengue Transmission
Historically low incidence of dengue in southeast Asia and Latin America linked to COVID-19 restrictions suggests potential future interventions.
Developing a COVID-19 Antiviral for Treatment and Prevention
Dr. Simon Portsmouth of Shionogi discusses the trial results of their once-daily oral COVID-19 antiviral, S-217622, as well as the significance of the therapy as vaccine efficacy wanes in the age of Omicron.
Rifaximin Effective in Majority of Patients Recurrent CDI Who Do Not Respond to Metronidazole
About 65% of patients with metronidazole-resistant recurrent C difficile infection benefitted from taking rifaximin.
Doctor Visits Dipped During COVID-19, Especially for Low-Income Americans
Utilization of ambulatory care services declined during the COVID-19 pandemic, especially among socioeconomically disadvantaged Americans.