HCV / Hepatitis

Study explores the receptiveness to long-acting antiviral solutions in low- and middle-income countries.

The combination therapy’s developer, Atea Pharmaceuticals, is looking to initiate a phase 3 study in early 2025.

This study explores HLA-E as a target to activate the immune system in HBV infection, identifying a stable peptide, Env371-379 L6I, that effectively triggers T-cell responses.

Patients with autoimmune hepatitis who are deficient in vitamin D had worse outcomes than patients with normal vitamin D levels.

Investigators highlighted the long-term cost-effectiveness of routine HCV screening as well as linkage-to-care for high-risk patients in emergency departments.

Recent studies show oral vancomycin reduces CDI by 64% in stem cell transplant patients, Biktarvy is effective for HIV/HBV co-infection, climate change drives rising dengue cases, and a 7-day antibiotic regimen is as effective as 14 days for bloodstream infections.

The country’s program yielded screening and treatment in almost two thirds of the identified at-risk population.

The ALLIANCE Phase III study demonstrated that Biktarvy, a TAF-based regimen, achieved sustained virologic suppression in adults with HIV/HBV co-infection.

Atea Pharmaceuticals has been reporting data on its combination of bemnifosbuvir and ruzasvir as a potential treatment for the virus.

The monoclonal antibody’s manufacturer, Bluejay Therapeutics, also reports in its phase 2 clinical trial there was up to a78% combined virologic response and ALT normalization as monotherapy.

Participants who used fentanyl were 1.64 times more likely to experience HCV seroconversion compared to those who did not.

Results suggest a shorter treatment duration could reduce costs and improve access in low- and middle-income countries.

Survey data show pharmacists are integral to HCV screening and treatment across healthcare settings, highlighting their contributions to HCV elimination efforts.

This week, a need for better access to diagnostic technologies for Long COVID, Iterium Therapeutics' discussed their FDA-approved Orlynvah for uncomplicated UTIs, the recent rise in human cases of avian influenza, and more.

HCV infection was associated with elevated brachial-ankle pulse wave velocity levels in patients with ESRD receiving hemodialysis.

Catherine Chappell, MD, MSc, presents what we know so far, highlighting the safety and effectiveness of direct-acting antivirals, the importance of shared decision-making, and the need for patient-provider discussions to ensure informed choices about care.

The Hawaii Department of Health released a report detailing the alarming link between hepatitis C and premature mortality in the state.

It is important to recognize this organ that has multiple life-enhancing functions.

The Xpert HCV assay facilitates rapid HCV diagnosis in nonclinical settings, aiding high-risk populations like those under community supervision.

This week, recent investigations link contaminated ice machines to Burkholderia multivorans infections, the hepatitis treatment market is projected to grow to USD 30.2 billion by 2032, 2020 guidelines recommend targeting specific AUC levels for optimizing vancomycin therapy, and more

A new study finds that 1.4 million people aged 12-59 with current hepatitis C (HCV) infection, including over a third of them without a history of injection drug use.

The global hepatitis treatment market is more than a financial figure; it is a key area in the effort to combat the silent disease that impacts millions around the world.

A systematic review and meta-analysis finds that hepatitis B (HBV) education led by healthcare providers had the greatest impact on testing uptake.

In 2015 the country's high prevalence of chronic hepatitis C (HCV) was 5.4%, higher than the global average of 1%. In addition, Georgia saw a 67% reduction in chronic infection.

The role of Anti-HDV IgG tests in diagnosing HDV in patients with Hepatitis B, showing sensitivity and specificity, making these serological tests important for identifying this form of viral hepatitis.

The model predicts and stratifies hepatocellular carcinoma risk by analyzing serum HBV DNA levels and other factors to enhance early detection and management.

A recent study showed that an increase in anti-hepatitis E virus seroprevalence in patients with chronic inflammatory demyelinating polyneuropathy was not a consequence of intravenous immunoglobulin therapy.

Overall, findings demonstrated a 78% treatment success rate among patients who prematurely discontinued direct-acting antivirals (DAA), and even seeing a 93% success rate among those who discontinued after week 4.

Protein organization could pave the way for effective vaccine development

The gene USP26 is identified as a factor in hepatocellular carcinoma development and a potential therapeutic target.